SCHEMBL1713103

SCHEMBL1713103

C#COC(=O)c1ccc(C(=O)Oc2cccc3ccccc23)o1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.57
HSD17B10 Q99714 3/20 0.57
RAB9A P51151 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
MEN1 O00255 1/20 0.49
MMP2 P08253 1/20 0.47
ALDH1A1 P00352 5/20 0.47
GAA P10253 3/20 0.47
PGR P06401 1/20 0.47
PTGS1 P23219 1/20 0.47
MAPK1 P28482 1/20 0.47
MAPT P10636 4/20 0.46
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ALOX5 P09917 2/20 0.45
PTGES O14684 1/20 0.45
POLB P06746 1/20 0.44
KDM4E B2RXH2 3/20 0.44
HPGD P15428 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1713094 0.84 ALOX5 (0.52) KMT2AHSD17B10RAB9AL3MBTL1MEN1
SCHEMBL1712749 0.82 ALOX5 (0.59) KMT2AHSD17B10RAB9AL3MBTL1MEN1
SCHEMBL1713044 0.77 KMT2A (0.46) KMT2AHSD17B10RAB9AL3MBTL1ALDH1A1
SCHEMBL7971452 0.73 KMT2A (0.58) KMT2AHSD17B10RAB9AL3MBTL1MEN1
SCHEMBL2255538 0.73 KMT2A (0.48) KMT2AHSD17B10RAB9AL3MBTL1MEN1
SCHEMBL1043660 0.73 ALOX5 (0.63) KMT2AHSD17B10RAB9AL3MBTL1MEN1
SCHEMBL3757751 0.73 KMT2A (0.70) KMT2AHSD17B10RAB9AL3MBTL1MEN1
SCHEMBL2262255 0.72 KMT2A (0.47) KMT2AHSD17B10RAB9AL3MBTL1MEN1
SCHEMBL2256429 0.72 KMT2A (0.47) KMT2AHSD17B10RAB9AL3MBTL1MEN1
SCHEMBL8367791 0.72 KMT2A (0.78) KMT2AHSD17B10RAB9AL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2344568-B1 ACETYLENIC POLYAMIDE NEXAM CHEMICAL AB (SE) 2017-12-20 EP claimed
US-8492507-B2 Acetylenic polyamide NEXAM CHEMICAL AB (SE) 2013-07-23 US claimed
US-20110190469-A1 ACETYLENIC POLYAMIDE NEXAM CHEMICAL AB (SE) 2011-08-04 US claimed
EP-2344568-A1 ACETYLENIC POLYAMIDE Nexam Chemical AB (SE) 2011-07-20 EP claimed
WO-2010036170-A1 ACETYLENIC POLYAMIDE NEXAM CHEMICAL AB (SE) 2010-04-01 WO claimed
EP-2344568-B1 ACETYLENIC POLYAMIDE NEXAM CHEMICAL AB (SE) 2017-12-20 EP disclosed
US-8492507-B2 Acetylenic polyamide NEXAM CHEMICAL AB (SE) 2013-07-23 US disclosed
US-20110190469-A1 ACETYLENIC POLYAMIDE NEXAM CHEMICAL AB (SE) 2011-08-04 US disclosed
EP-2344568-A1 ACETYLENIC POLYAMIDE Nexam Chemical AB (SE) 2011-07-20 EP disclosed
WO-2010036170-A1 ACETYLENIC POLYAMIDE NEXAM CHEMICAL AB (SE) 2010-04-01 WO disclosed