SCHEMBL17131749

SCHEMBL17131749

CCC(C)C(=O)OCCCCOc1ccc(C(=O)Oc2ccc(C(=O)Oc3ccc(N=Nc4ccc(N(CC)CC)cc4)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRSS1 P07477 3/20 0.47
▸ ACR P10323 3/20 0.47
▸ NPC1 O15118 3/20 0.42
▸ LMNA P02545 3/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ CYP2D6 P10635 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ NFKB1 P19838 3/20 0.42
▸ NFKB2 Q00653 3/20 0.42
▸ RELA Q04206 3/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ ALDH1A1 P00352 2/20 0.40
▸ MAPT P10636 5/20 0.39
▸ KMT2A Q03164 4/20 0.39
▸ TSHR P16473 1/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17694528 1.00 PRSS1 (0.47) PRSS1ACRNPC1LMNACYP1A2
SCHEMBL17694530 1.00 PRSS1 (0.47) PRSS1ACRNPC1LMNACYP1A2
SCHEMBL26033899 0.99 PRSS1 (0.47) PRSS1ACRNPC1LMNACYP1A2
SCHEMBL17694531 0.92 PPARA (0.40) NPC1LMNASMN1; SMN2MAPTKMT2A
SCHEMBL19267453 0.88 PRSS1 (0.37) PRSS1ACRALDH1A1MAPTKMT2A
SCHEMBL19267457 0.88 PRSS1 (0.37) PRSS1ACRALDH1A1MAPTKMT2A
SCHEMBL24555471 0.86 PRSS1 (0.52) PRSS1ACRNPC1LMNACYP1A2
SCHEMBL17694529 0.86 PRSS1 (0.49) PRSS1ACRNPC1LMNACYP1A2
SCHEMBL17131753 0.86 LMNA (0.58) PRSS1ACRNPC1LMNACYP1A2
SCHEMBL26034270 0.85 PRSS1 (0.51) PRSS1ACRNPC1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180045870-A1 TRANSPARENT FILM, POLARIZING PLATE, AND IMAGE DISPLAYING DEVICE FUJIFILM CORPORATION (JP) 2018-02-15 — — US disclosed
US-20170242175-A1 RETARDATION FILM, COMPOSITION, METHOD OF MANUFACTURING RETARDATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-08-24 — — US disclosed
US-9726798-B2 Optical film, polarizing plate, and method for producing optical film FUJIFILM CORPORATION (JP) 2017-08-08 — — US disclosed
US-9678384-B2 Retardation film, composition, method of manufacturing retardation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-06-13 — — US disclosed
US-20160109757-A1 RETARDATION FILM, COMPOSITION, METHOD OF MANUFACTURING RETARDATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-04-21 — — US disclosed
US-20150277006-A1 OPTICAL FILM, POLARIZING PLATE, AND METHOD FOR PRODUCING OPTICAL FILM FUJIFILM CORPORATION (JP) 2015-10-01 — — US disclosed
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