Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 12/20 | 0.69 |
| ▸ | NPC1 | O15118 | 11/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17107250 | 1.00 | RAB9A (0.69) | RAB9AALDH1A1SMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL17107251 | 1.00 | RAB9A (0.69) | RAB9AALDH1A1SMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL17132026 | 0.91 | RAB9A (0.68) | RAB9AALDH1A1SMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL17107242 | 0.91 | RAB9A (0.68) | RAB9AALDH1A1SMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL17107243 | 0.91 | RAB9A (0.68) | RAB9AALDH1A1SMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL13428993 | 0.77 | RAB9A (0.76) | RAB9AALDH1A1SMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL5708565 | 0.76 | KMT2A (0.60) | RAB9AALDH1A1SMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL5281141 | 0.74 | NPC1 (0.51) | RAB9AALDH1A1SMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL17107260 | 0.72 | SMN1; SMN2 (0.69) | RAB9AALDH1A1SMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL17107261 | 0.72 | SMN1; SMN2 (0.69) | RAB9AALDH1A1SMN1; SMN2NPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210330646-A1 | FASCIN BINDING COMPOUNDS FOR SPINOGENESIS | SPINOGENIX, INC. | 2021-10-28 | — | — | US | disclosed |
| US-9650369-B2 | Anti-migration and anti-invasion thiazole analogs for treatment of cellular proliferative disease | XAVIER UNIVERSITY OF LOUISIANA (US) | 2017-05-16 | — | — | US | disclosed |
| US-9650369-B2 | Anti-migration and anti-invasion thiazole analogs for treatment of cellular proliferative disease | XAVIER UNIVERSITY OF LOUISIANA (US) | 2017-05-16 | — | — | US | disclosed |
| US-20150274714-A1 | ANTI-MIGRATION AND ANTI-INVASION THIAZOLE ANALOGS FOR TREATMENT OF CELLULAR PROLIFERATIVE DISEASE | XAVIER UNIVERSITY OF LOUISIANA | 2015-10-01 | — | — | US | disclosed |
| US-20150274714-A1 | ANTI-MIGRATION AND ANTI-INVASION THIAZOLE ANALOGS FOR TREATMENT OF CELLULAR PROLIFERATIVE DISEASE | XAVIER UNIVERSITY OF LOUISIANA | 2015-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274714-A1 | ANTI-MIGRATION AND ANTI-INVASION THIAZOLE ANALOGS FOR TREATMENT OF CELLULAR PROLIFERATIVE DISEASE | MKI67, MIF, NUDC | RAB9A 1305/4885ALDH1A1 1082/4885SMN1; SMN2 2720/4885 |
| US-20210330646-A1 | FASCIN BINDING COMPOUNDS FOR SPINOGENESIS | FSCN1, SMN1; SMN2, DCX | RAB9A 931/4885ALDH1A1 3791/4885SMN1; SMN2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.