Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.70 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.70 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.70 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.66 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | CTSD | P07339 | 1/20 | 0.66 |
| ▸ | PTPRF | P10586 | 1/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.66 |
| ▸ | CETP | P11597 | 1/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.66 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.66 |
| ▸ | CES1 | P23141 | 1/20 | 0.66 |
| ▸ | ACP1 | P24666 | 1/20 | 0.66 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.66 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976687 | 1.00 | EGLN2 (0.70) | EGLN2EGLN1EGLN3P4HTMPTPN1 | |
| SCHEMBL19976698 | 1.00 | EGLN2 (0.70) | EGLN2EGLN1EGLN3P4HTMPTPN1 | |
| SCHEMBL17133035 | 1.00 | EGLN2 (0.70) | EGLN2EGLN1EGLN3P4HTMPTPN1 | |
| SCHEMBL17030502 | 0.92 | EGLN2 (0.58) | EGLN2EGLN1EGLN3P4HTMPTPN1 | |
| SCHEMBL24190850 | 0.87 | PTPN1 (0.69) | EGLN2EGLN1EGLN3P4HTMPTPN1 | |
| SCHEMBL17133043 | 0.87 | F3 (0.73) | EGLN2EGLN1EGLN3P4HTMPTPN1 | |
| SCHEMBL17030493 | 0.87 | F3 (0.73) | EGLN2EGLN1EGLN3P4HTMPTPN1 | |
| SCHEMBL19976668 | 0.87 | F3 (0.73) | EGLN2EGLN1EGLN3P4HTMPTPN1 | |
| SCHEMBL24190889 | 0.87 | PTPN1 (0.69) | EGLN2EGLN1EGLN3P4HTMPTPN1 | |
| SCHEMBL19976677 | 0.87 | F3 (0.73) | EGLN2EGLN1EGLN3P4HTMPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150274766-A1 | Triterpene Derivative and Its Anti-Influenza Use | PEKING UNIVERSITY (CN) | 2015-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274766-A1 | Triterpene Derivative and Its Anti-Influenza Use | HAVCR2, MAVS, IRF3 | EGLN2 1495/4885EGLN1 1821/4885EGLN3 1043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.