Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2566017 | 0.93 | EPHX1 (0.47) | EPHX1TSHRCA12CA1CA2 | |
| SCHEMBL2561394 | 0.91 | EPHX1 (0.48) | EPHX1TSHRCA12CA1CA2 | |
| SCHEMBL17133262 | 0.91 | EPHX1 (0.33) | EPHX1 | |
| SCHEMBL4419366 | 0.89 | EPHX1 (0.47) | EPHX1TSHRCA12CA1CA2 | |
| SCHEMBL17133238 | 0.88 | EPHX1 (0.55) | EPHX1EPHX2ATM | |
| SCHEMBL12794861 | 0.88 | EPHX1 (0.42) | EPHX1TSHRCA12CA1CA2 | |
| SCHEMBL4362272 | 0.87 | EPHX1 (0.55) | EPHX1CA12CA1CA2CA9 | |
| SCHEMBL4355762 | 0.86 | EPHX1 (0.57) | EPHX1EPHX2 | |
| SCHEMBL21360055 | 0.86 | EPHX1 (0.44) | EPHX1TSHRCA12CA1CA2 | |
| SCHEMBL28435450 | 0.86 | EPHX1 (0.55) | EPHX1EPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015144384-A1 | SILANE CONTAINING RESPECTIVELY AT LEAST TWO ALKOXY GROUPS AND A GUANIDONO OR CARBAMIDE GROUP | EVONIK DEGUSSA GMBH (DE) | 2015-10-01 | — | — | WO | disclosed |