SCHEMBL4419366

SCHEMBL4419366

CCO[Si](CCCNC(=O)NCCNC(=O)NCCC[Si](OCC)(OCC)OCC)(OCC)OCC

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 8/20 0.47
PRMT1 Q99873 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
TSHR P16473 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
EPHX2 P34913 1/20 0.35
ACHE P22303 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2561394 0.98 EPHX1 (0.48) EPHX1PRMT1CA12CA1CA2
SCHEMBL4362272 0.94 EPHX1 (0.55) EPHX1PRMT1CA12CA1CA2
SCHEMBL4355762 0.92 EPHX1 (0.57) EPHX1EPHX2ACHE
SCHEMBL21360055 0.92 EPHX1 (0.44) EPHX1PRMT1CA12CA1CA2
SCHEMBL28435450 0.92 EPHX1 (0.55) EPHX1MEN1KMT2AEPHX2ACHE
SCHEMBL19838195 0.92 EPHX1 (0.52) EPHX1PRMT1CA12CA1CA2
SCHEMBL4355837 0.91 EPHX1 (0.42) EPHX1PRMT1CA12CA1CA2
SCHEMBL11215980 0.89 EPHX1 (0.41) EPHX1PRMT1CA12CA1CA2
SCHEMBL21360054 0.89 EPHX1 (0.56) EPHX1EPHX2ACHE
SCHEMBL12190469 0.89 EPHX1 (0.41) EPHX1PRMT1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230313033-A1 Nanoparticles To Improve Analytical Signal Alma Mater Studiorum - Università di Bologna (IT) 2023-10-05 US disclosed
US-20230313033-A1 Nanoparticles To Improve Analytical Signal Alma Mater Studiorum - Università di Bologna (IT) 2023-10-05 US disclosed
EP-4211079-A1 NANOPARTICLES TO IMPROVE ANALYTICAL SIGNAL Alma Mater Studiorum Universita di Bologna (IT) 2023-07-19 EP disclosed
WO-2022053965-A1 NANOPARTICLES TO IMPROVE ANALYTICAL SIGNAL ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA (IT) 2022-03-17 WO disclosed
US-10941341-B2 Etching composition additive, method for preparing the same and etching composition comprising the same SK INNOVATION CO., LTD. (KR) 2021-03-09 US disclosed
US-10781371-B2 Etchant composition and silane compound SK INNOVATION CO., LTD. (KR) 2020-09-22 US disclosed
US-20200131438-A1 ETCHING COMPOSITION ADDITIVE, METHOD FOR PREPARING THE SAME AND ETCHING COMPOSITION COMPRISING THE SAME SK INNOVATION CO., LTD. (KR) 2020-04-30 US disclosed
EP-2138501-B1 Functional silane compound, coating solution, and method for manufacturing plastic lens HOYA CORP (JP) 2014-08-13 EP disclosed
US-20090317541-A1 FUNCTIONAL SILANE COMPOUND, COATING SOLUTION, AND METHOD FOR MANUFACTURING PLASTIC LENS HOYA CORPORATION (JP) 2009-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10781371-B2 Etchant composition and silane compound H1-0, H1-5, ALOX5 EPHX1 298/4885PRMT1 681/4885CA12 826/4885
US-20090317541-A1 FUNCTIONAL SILANE COMPOUND, COATING SOLUTION, AND METHOD FOR MANUFACTURING PLASTIC LENS SUMO1, CAD, UFM1 EPHX1 4148/4885PRMT1 798/4885CA12 1285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.