SCHEMBL17133252

SCHEMBL17133252

CCCCNC(=O)N(CCN)CCC[Si](C)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACHE P22303 8/20 0.33
DPP7 Q9UHL4 1/20 0.32
EPHX1 P07099 3/20 0.32
RRM1 P23921 1/20 0.31
MMP2 P08253 1/20 0.30
GNAI3 P08754 1/20 0.30
GNAO1 P09471 1/20 0.30
GNAI1 P63096 1/20 0.30
BCHE P06276 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17133212 0.88 ACHE (0.34) ACHEDPP7EPHX1RRM1MMP2
SCHEMBL17133237 0.88 ACHE (0.34) ACHEDPP7EPHX1RRM1MMP2
SCHEMBL2558404 0.87 CA12 (0.31)
SCHEMBL17133270 0.87 EPHX1 (0.41) ACHEEPHX1
SCHEMBL17133226 0.85
SCHEMBL2616730 0.84 ACHE (0.33) ACHEEPHX1ALDH1A1
SCHEMBL17133208 0.81 ACHE (0.35) ACHEDPP7EPHX1RRM1MMP2
SCHEMBL17133234 0.80
SCHEMBL15906240 0.77 EPHX1 (0.48) DPP7EPHX1RRM1GNAI3GNAO1
SCHEMBL17133277 0.77 HDAC6 (0.43) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015144384-A1 SILANE CONTAINING RESPECTIVELY AT LEAST TWO ALKOXY GROUPS AND A GUANIDONO OR CARBAMIDE GROUP EVONIK DEGUSSA GMBH (DE) 2015-10-01 WO disclosed