SCHEMBL17135342

SCHEMBL17135342

CCOC(=O)CO[PH](=O)OCC

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.46
MGAM O43451 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
ALDH1A1 P00352 3/20 0.43
TRPA1 O75762 1/20 0.43
NLRP3 Q96P20 4/20 0.39
TSHR P16473 1/20 0.38
CYP1A2 P05177 1/20 0.38
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
ALOX15 P16050 1/20 0.36
SOAT1 P35610 1/20 0.36
KMT2A Q03164 1/20 0.35
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3618713 0.96 GAA (0.50) GAAMGAMSIMGAM2ALDH1A1
Succinic Acid Diethyl Ester SCHEMBL28409299 0.84 CYP1A2 (0.48) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL3618711 0.80 GAA (0.48) GAAMGAMSIMGAM2ALDH1A1
Ethyl Acetate SCHEMBL7247574 0.77 ALDH1A1 (0.67) GAAMGAMSIMGAM2ALDH1A1
Butane SCHEMBL5481709 0.77 GAA (0.44) GAAMGAMSIMGAM2ALDH1A1
Acetone SCHEMBL11340080 0.76 ALDH1A1 (0.41) GAAMGAMSIMGAM2ALDH1A1
Methyl Alcohol SCHEMBL11431123 0.75 ALDH1A1 (0.33) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL3974885 0.75 KMT2A (0.30) ALDH1A1TSHRKMT2A
SCHEMBL35436 0.75
Alcohol SCHEMBL27677214 0.73 ALDH1A1 (0.38) ALDH1A1TSHRLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2927279-A1 FLAME-RETARDANT POLYBUTYLENE TEREPHTHALATE RESIN COMPOSITION, AND MOLDED PRODUCT THEREOF Wintech Polymer Ltd. (JP) 2015-10-07 EP disclosed