⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16120050 | 1.00 | — | — | |
| SCHEMBL14491025 | 1.00 | — | — | |
| SCHEMBL14330784 | 1.00 | — | — | |
| SCHEMBL68223 | 0.84 | — | — | |
| SCHEMBL19619643 | 0.84 | — | — | |
| SCHEMBL636499 | 0.84 | — | — | |
| SCHEMBL13977823 | 0.83 | — | — | |
| SCHEMBL18234215 | 0.83 | — | — | |
| SCHEMBL21154997 | 0.83 | PLG (0.44) | — | |
| SCHEMBL8274293 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1095 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103257189-B | (S)-MNTX, its synthetic method with and medicinal usage | PROGENICS PHARM INC. (US) | 2016-05-11 | — | — | CN | claimed |
| CN-101208345-B | (S) -N-methylnaltrexone, method of synthesis and pharmaceutical use thereof | PROGENICS PHARM INC | 2013-10-16 | — | — | CN | claimed |
| EP-1928882-B1 | (S)-N-METHYLNALTREXONE, PROCESS FOR ITS SYNTHESIS AND ITS PHARMACEUTICAL USE | PROGENICS PHARM INC (US) | 2013-09-04 | — | — | EP | claimed |
| CN-102838533-A | Preparation method of roflumilast and key intermediate of roflumilast | BEIJING D VENTURE PHARM TECH | 2012-12-26 | — | — | CN | claimed |
| US-20120136019-A1 | (S)-N-METHYLNALTREXONE | PROGENICS PHARMACEUTICALS, INC. (US) | 2012-05-31 | — | — | US | claimed |
| EP-2450360-A2 | (S)-N-Methylnaltrexone | Progenics Pharmaceuticals, Inc. (US) | 2012-05-09 | — | — | EP | claimed |
| US-8003794-B2 | (S)-N-methylnaltrexone | PROGENICS PHARMACEUTICALS, INC. (US) | 2011-08-23 | — | — | US | claimed |
| CN-101955484-A | Method for synthesizing naloxone or naltrexone | GANSU PUAN PHARMACEUTICALS CO LTD | 2011-01-26 | — | — | CN | claimed |
| US-20100105911-A1 | (S)-N-methylnal trexone | ALBANY MOLECULAR RESEARCH, INC. | 2010-04-29 | — | — | US | claimed |
| CN-100420379-C | Stable ethene in hibitory compound and its prepn method | ROHM & HAAS (US) | 2008-09-24 | — | — | CN | claimed |
| CN-101208345-A | (S) -N-methylnaltrexone, method of synthesis and pharmaceutical use thereof | PROGENICS PHARM INC (US) | 2008-06-25 | — | — | CN | claimed |
| EP-1928882-A2 | (S)-N-METHYLNALTREXONE, PROCESS FOR ITS SYNTHESIS AND ITS PHARMACEUTICAL USE | PROGENICS PHARMACEUTICALS, INC. (US) | 2008-06-11 | — | — | EP | claimed |
| US-20070265293-A1 | Opioid antagonists; lyophilization | PROGENICS PHARMACEUTICAIS, INC. | 2007-11-15 | — | — | US | claimed |
| WO-2006127898-A2 | (S)-N-METHYLNALTREXONE, PROCESS FOR ITS SYNTHESIS AND ITS PHARMACEUTICAL USE | PROGENICS PHARMACEUTICALS, INC. (US) | 2006-11-30 | — | — | WO | claimed |
| CN-1480438-A | Stable ethene in hibitory compound and its prepn method | ��������ķ������ | 2004-03-10 | — | — | CN | claimed |
| JP-9255648-A | — | — | None | — | — | JP | disclosed |
| EP-4746963-A1 | MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| US-4065480-A | Process for preparing substituted cyclopropycarbinyl compounds | THE PROCTER & GAMBLE COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-3998889-A | REACTING AN UNSATURATED ORGANO-TIN COMPOUND WITH AN ORGANIC SULFUR HALIDE | THE PROCTER & GAMBLE COMPANY (US) | 1976-12-21 | — | — | US | disclosed |
| US-3959324-A | PESTICIDE, ANTIINFLAMMATORY | THE PROCTER & GAMBLE COMPANY (US) | 1976-05-25 | — | — | US | disclosed |