SCHEMBL636499

SCHEMBL636499

ICC1CCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68223 0.92
SCHEMBL2652702 0.89
SCHEMBL172670 0.89
SCHEMBL2653714 0.89 CHRM5 (0.39)
Hydrogen Sulfide SCHEMBL11077832 0.86
SCHEMBL9837405 0.86
SCHEMBL18948737 0.86
SCHEMBL171373 0.84
SCHEMBL14330784 0.84
SCHEMBL14491025 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103387510-B A kind of synthetic method of beta-amino-alpha-hydroxycyclobutyl butanamide hydrochloride SUZHOU UUGENE BIOPHARMA CO., LTD. (CN) 2015-09-09 CN claimed
CN-103387510-A Synthesis method of beta-amino-alpha-hydroxycyclohexyl butyl aluminum hydrochloride SUZHOU UUGENE BIOPHARMA CO LTD 2013-11-13 CN claimed
WO-2026107328-A1 AGONISTS OF PARATHYROID HORMONE 1 AND INCRETIN RECEPTORS SEPTERNA, INC. (US) 2026-05-21 WO disclosed
EP-4308096-B1 HETEROAROYL AMIDES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF MERCK SHARP & DOHME LLC (US) 2026-05-13 EP disclosed
EP-4541794-A1 PHENYL-SUBSTITUTED DIHYDRONAPHTHYRIDINE COMPOUNDS, AND PREPARATION AND USE THEREOF Suzhong Pharmaceutical Group Co., Ltd. (CN) 2025-04-23 EP disclosed
WO-2025076284-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 WO disclosed
CN-119585263-A Phenyl substituted dihydro Cai compounds and preparation and application thereof 苏中药业集团股份有限公司 2025-03-07 CN disclosed
CN-119431358-A Pyrrolopyridines, compositions thereof and their use in medicine 中国科学院上海药物研究所 2025-02-14 CN disclosed
WO-2025011008-A1 PHARMACEUTICAL PREPARATION CONTAINING PHENYL-SUBSTITUTED DIHYDRONAPHTHYRIDINE COMPOUND, AND USE THEREOF 苏中药业集团股份有限公司 2025-01-16 WO disclosed
CN-119302952-A Pharmaceutical preparation containing phenyl substituted dihydronaphthyridine compound and application thereof 苏中药业集团股份有限公司 2025-01-14 CN disclosed
CN-119306715-A Crystal of phenyl substituted dihydronaphthyridine compound and application thereof 苏中药业集团股份有限公司 2025-01-14 CN disclosed
WO-1996007405-A1 EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1996-03-14 WO disclosed
CN-1017900-B PROCESS FOR PRODUCTION OF ELLIPTICINE DERIVATIVE SUNTORY LTD (JP) 1992-08-19 CN disclosed
EP-0173462-B1 ELLIPTICINE DERIVATIVE AND PRODUCTION PROCESS THEREOF SUNTORY LIMITED (JP) 1989-10-25 EP disclosed
US-4698423-A ANTITUMOR AGENTS SUNTORY LIMITED (JP) 1987-10-06 US disclosed
CN-85107911-A The production method of ellipticine derivative 1987-02-25 CN disclosed
EP-0173462-A2 Ellipticine derivative and production process thereof SUNTORY LIMITED (JP) 1986-03-05 EP disclosed
US-4337341-A 4a-Aryl-octahydro-1H-2-pyrindines ELI LILLY AND COMPANY (US) 1982-06-29 US disclosed
EP-0002937-A1 Novel pyrindines and their preparation, formulations and use ELI LILLY AND COMPANY (US) 1979-07-11 EP disclosed
US-4141893-A Decahydrocyclopent[c]azepines ELI LILLY AND COMPANY (US) 1979-02-27 US disclosed