SCHEMBL1713752

SCHEMBL1713752

O=C(O)COc1ccc(Cl)cc1CN1CCN(C(=O)Cc2ccc(F)cc2)CC1

nearest known ligand 0.83

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 16/20 0.83
CCR1 P32246 1/20 0.52
MGLL Q99685 1/20 0.52
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1714400 0.94 PTGDR2 (0.90) PTGDR2MGLL
SCHEMBL1713709 0.90 PTGDR2 (0.83) PTGDR2
SCHEMBL1714022 0.88 PTGDR2 (0.80) PTGDR2MEN1KMT2A
SCHEMBL1713880 0.87 PTGDR2 (0.79) PTGDR2MGLL
SCHEMBL1714179 0.87 PTGDR2 (0.92) PTGDR2MEN1KMT2A
SCHEMBL13800214 0.87 PTGDR2 (0.88) PTGDR2MEN1KMT2A
SCHEMBL13800284 0.87 PTGDR2 (0.77) PTGDR2MGLLMEN1KMT2A
SCHEMBL1714226 0.85 PTGDR2 (0.60) PTGDR2MEN1KMT2A
SCHEMBL1713638 0.84 PTGDR2 (1.00) PTGDR2CCR1
SCHEMBL13800244 0.84 MEN1 (0.58) PTGDR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8524715-B2 Phenoxyacetic acid derivatives useful for treating respiratory diseases ASTRAZENECA AB (SE) 2013-09-03 US claimed
EP-1817282-B1 PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES ASTRAZENECA AB (SE) 2011-07-20 EP claimed
US-20090149448-A1 Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases ASTRAZENECA AB (SE) 2009-06-11 US claimed
US-8524715-B2 Phenoxyacetic acid derivatives useful for treating respiratory diseases ASTRAZENECA AB (SE) 2013-09-03 US disclosed
EP-1817282-B1 PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES ASTRAZENECA AB (SE) 2011-07-20 EP disclosed
US-20090149448-A1 Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases ASTRAZENECA AB (SE) 2009-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149448-A1 Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases PAOX, PCCA, PAH PTGDR2 236/4885CCR1 1747/4885MGLL 1505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.