Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048430 | 0.74 | ALDH1A3 (0.62) | ALDH1A3DRD1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL16353393 | 0.73 | ALDH1A3 (0.66) | ALDH1A3DRD1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL7686959 | 0.71 | ALDH1A3 (0.58) | ALDH1A3DRD1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL11684015 | 0.71 | ALDH1A3 (0.58) | ALDH1A3DRD1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL28432315 | 0.71 | ALDH1A3 (0.58) | ALDH1A3DRD1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL12318700 | 0.71 | ALDH1A3 (0.58) | ALDH1A3DRD1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL6317305 | 0.69 | ALDH1A3 (0.55) | ALDH1A3DRD1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL1915714 | 0.68 | ALDH1A3 (0.58) | ALDH1A3DRD1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL19435692 | 0.68 | PDE2A (0.54) | ALDH1A3ALDH1A1CYP2A6ALDH3A1TYR | |
| SCHEMBL14016002 | 0.68 | ALDH1A3 (0.76) | ALDH1A3DRD1ALDH1A1CYP2A6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9770420-B2 | Method for producing a polyglycerol nanogel for the encapsulation and release of biologically active substances | FREIE UNIVERSITÄT BERLIN (DE) | 2017-09-26 | — | — | US | disclosed |
| US-20150283094-A1 | METHOD FOR PRODUCING A POLYGLYCEROL NANOGEL FOR THE ENCAPSULATION AND RELEASE OF BIOLOGICALLY ACTIVE SUBSTANCES | FREIE UNIVERSITÄT BERLIN (DE) | 2015-10-08 | — | — | US | disclosed |