SCHEMBL17138128

SCHEMBL17138128

CCCCCCCC(=O)Oc1c(OC(=O)CCCCCCC)c(OC(=O)CCCCCCC)c2ccccc2c1OC(=O)CCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.50
KMT2A Q03164 2/20 0.49
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
RECQL P46063 1/20 0.49
POLM Q9NP87 1/20 0.48
POLK Q9UBT6 1/20 0.48
POLL Q9UGP5 1/20 0.48
POLH Q9Y253 1/20 0.48
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
PAM P19021 2/20 0.46
DGKA P23743 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
EP300 Q09472 1/20 0.44
ALOX15 P16050 1/20 0.44
FAAH O00519 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29371710 0.95 EPHX2 (0.51) EPHX2KMT2AKDM4EMEN1RECQL
SCHEMBL29372133 0.95 EPHX2 (0.51) EPHX2KMT2AKDM4EMEN1RECQL
SCHEMBL30003164 0.95 EPHX2 (0.51) EPHX2KMT2AKDM4EMEN1RECQL
SCHEMBL20398671 0.95 EPHX2 (0.51) EPHX2KMT2AKDM4EMEN1RECQL
SCHEMBL20398590 0.95 EPHX2 (0.51) EPHX2KMT2AKDM4EMEN1RECQL
SCHEMBL23271733 0.95 EPHX2 (0.51) EPHX2KMT2AKDM4EMEN1RECQL
SCHEMBL20398624 0.95 EPHX2 (0.51) EPHX2KMT2AKDM4EMEN1RECQL
SCHEMBL29370938 0.95 EPHX2 (0.51) EPHX2KMT2AKDM4EMEN1RECQL
SCHEMBL29360726 0.95 EPHX2 (0.51) EPHX2KMT2AKDM4EMEN1RECQL
SCHEMBL29368355 0.95 EPHX2 (0.51) EPHX2KMT2AKDM4EMEN1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150283051-A1 DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF RNS CO.,LTD. (KR) 2015-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150283051-A1 DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF HRH3, CBR3, H1-0 EPHX2 3034/4885KMT2A 580/4885KDM4E 494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.