Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17138142 | 1.00 | TSHR (0.46) | TSHRKMT2AMAPK1CYP1A2CYP2D6 | |
| SCHEMBL3775414 | 0.85 | MAOB (0.43) | TSHRPPARA | |
| SCHEMBL3661681 | 0.85 | APP (0.48) | TSHRKMT2AMAPK1CYP1A2CYP2D6 | |
| SCHEMBL3775410 | 0.85 | APP (0.48) | TSHRKMT2AMAPK1CYP1A2CYP2D6 | |
| SCHEMBL17138207 | 0.85 | AOC3 (0.44) | TSHRKMT2AMAPK1CYP1A2CYP2D6 | |
| SCHEMBL17138209 | 0.85 | AOC3 (0.44) | TSHRKMT2AMAPK1CYP1A2CYP2D6 | |
| SCHEMBL17138216 | 0.79 | MAPK1 (0.49) | TSHRMAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL17138217 | 0.79 | MAPK1 (0.49) | TSHRMAPK1CYP1A2CYP2D6CYP2C19 | |
| 1,3-Dipropoxybenzene SCHEMBL73716 | 0.79 | KMT2A (0.63) | TSHRKMT2AMAPK1CYP1A2CYP2D6 | |
| SCHEMBL25264767 | 0.79 | DRD2 (0.49) | KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150283051-A1 | DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF | RNS CO.,LTD. (KR) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150283051-A1 | DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF | HRH3, CBR3, H1-0 | TSHR 4026/4885KMT2A 580/4885MAPK1 1198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.