Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17138127 | 0.89 | CYP3A4 (0.49) | HIF1ATSHRMAPK1CYP3A4 | |
| SCHEMBL17031447 | 0.89 | GPBAR1 (0.48) | HIF1ATSHRMAPK1GPBAR1MTNR1A | |
| SCHEMBL17031446 | 0.89 | GPBAR1 (0.48) | HIF1ATSHRMAPK1GPBAR1MTNR1A | |
| SCHEMBL17138204 | 0.88 | TSHR (0.49) | HIF1ATSHRMAPK1KDM4EGPBAR1 | |
| SCHEMBL28029167 | 0.87 | LMNA (0.50) | CYP3A4MTNR1AMTNR1B | |
| SCHEMBL4568773 | 0.86 | KMT2A (0.49) | HIF1ATSHRMAPK1KDM4EGPBAR1 | |
| SCHEMBL17032380 | 0.85 | GPBAR1 (0.40) | HIF1ATSHRMAPK1GPBAR1MTNR1A | |
| SCHEMBL4569083 | 0.85 | GPBAR1 (0.40) | HIF1ATSHRMAPK1GPBAR1MTNR1A | |
| SCHEMBL11993596 | 0.85 | MAPK1 (0.46) | HIF1ATSHRMAPK1GPBAR1TP53 | |
| SCHEMBL20318730 | 0.85 | PPARA (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150283051-A1 | DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF | RNS CO.,LTD. (KR) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150283051-A1 | DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF | HRH3, CBR3, H1-0 | HIF1A 375/4885TSHR 4026/4885MAPK1 1198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.