SCHEMBL17138157

SCHEMBL17138157

CCCCC(=O)Oc1cccc(OC(=O)CCCC)c1

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
MEN1 O00255 3/20 0.53
ALDH1A1 P00352 1/20 0.53
MAPK1 P28482 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
KDM4E B2RXH2 1/20 0.53
RECQL P46063 1/20 0.53
ACHE P22303 1/20 0.50
EGFR P00533 1/20 0.48
ERBB2 P04626 1/20 0.48
MTNR1A P48039 1/20 0.47
MTNR1B P49286 1/20 0.47
TP53 P04637 1/20 0.46
MAPT P10636 1/20 0.46
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10407331 0.95 KMT2A (0.60) KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1
SCHEMBL28188561 0.93 EGFR (0.56) KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1
SCHEMBL17138156 0.93 KMT2A (0.61) KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1
SCHEMBL9716543 0.93 KMT2A (0.61) KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1
SCHEMBL17138195 0.93 KMT2A (0.61) KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1
SCHEMBL17138196 0.93 KMT2A (0.61) KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1
SCHEMBL28584208 0.92 PLA2G4B (0.53) KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1
SCHEMBL572371 0.91 LMNA (0.59) KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1
SCHEMBL4079668 0.90 CYP3A4 (0.57) KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1
SCHEMBL421378 0.89 BCL9 (0.53) KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150283051-A1 DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF RNS CO.,LTD. (KR) 2015-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150283051-A1 DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF HRH3, CBR3, H1-0 KMT2A 580/4885SMN1; SMN2 1635/4885MEN1 4684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.