Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714940 | 0.85 | KDM4E (0.80) | KDM4EALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL28766926 | 0.85 | ALDH1A1 (0.56) | KDM4EALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL2931356 | 0.83 | ALDH1A1 (0.50) | KDM4EALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL13800284 | 0.82 | PTGDR2 (0.77) | KDM4EALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL9321429 | 0.82 | ALDH1A1 (0.75) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8377657 | 0.80 | CYP2D6 (0.65) | KDM4EALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL1714140 | 0.80 | KDM4E (0.62) | KDM4EALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL27852046 | 0.80 | KDM4E (0.62) | KDM4EALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL6681439 | 0.78 | ALDH1A1 (0.83) | KDM4EALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL1714246 | 0.77 | KMT2A (0.55) | KDM4EALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524715-B2 | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB (SE) | 2013-09-03 | — | — | US | disclosed |
| CN-101107226-B | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB | 2012-01-18 | — | — | CN | disclosed |
| EP-1817282-B1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2011-07-20 | — | — | EP | disclosed |