Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | RECQL | P46063 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.62 |
| ▸ | DRD2 | P14416 | 3/20 | 0.62 |
| ▸ | DRD1 | P21728 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | APEX1 | P27695 | 3/20 | 0.62 |
| ▸ | DRD4 | P21917 | 2/20 | 0.62 |
| ▸ | DRD5 | P21918 | 2/20 | 0.62 |
| ▸ | DRD3 | P35462 | 2/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HTR1A | P08908 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328576 | 1.00 | TDP1 (0.62) | TDP1TAAR1KDM4ERECQLMAPK1 | |
| Hydrochloric Acid SCHEMBL3757551 | 0.97 | TDP1 (0.64) | TDP1TAAR1KDM4ERECQLMAPK1 | |
| Water SCHEMBL17686500 | 0.97 | TDP1 (0.60) | TDP1TAAR1KDM4ERECQLMAPK1 | |
| Hydrochloric Acid SCHEMBL29134173 | 0.95 | TDP1 (0.58) | TDP1TAAR1KDM4ERECQLMAPK1 | |
| SCHEMBL69532 | 0.85 | TDP1 (0.54) | TDP1TAAR1KDM4ERECQLMAPK1 | |
| SCHEMBL20849682 | 0.84 | MAPK1 (0.46) | TDP1TAAR1KDM4ERECQLMAPK1 | |
| SCHEMBL28735818 | 0.84 | TAAR1 (0.52) | TDP1TAAR1KDM4ERECQLMAPK1 | |
| SCHEMBL29705208 | 0.84 | TAAR1 (0.52) | TDP1TAAR1KDM4ERECQLMAPK1 | |
| SCHEMBL10634508 | 0.84 | MAPK1 (0.52) | TDP1TAAR1KDM4ERECQLMAPK1 | |
| SCHEMBL5495349 | 0.84 | TAAR1 (0.52) | TDP1TAAR1KDM4ERECQLMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150284517-A1 | POLYMER LIGANDS FOR NANOPARTICLES | NATIONAL SCIENCE FOUNDATION | 2015-10-08 | — | — | US | claimed |
| US-20150284517-A1 | POLYMER LIGANDS FOR NANOPARTICLES | NATIONAL SCIENCE FOUNDATION | 2015-10-08 | — | — | US | disclosed |