SCHEMBL29705208

SCHEMBL29705208

NCCc1cc(O)c(O)c(Cl)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 7/20 0.52
KDM4E B2RXH2 3/20 0.52
ADRA2A P08913 3/20 0.52
SLC6A2 P23975 3/20 0.52
DRD2 P14416 3/20 0.52
DRD1 P21728 3/20 0.52
MAPK1 P28482 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
MAPT P10636 2/20 0.52
DRD4 P21917 2/20 0.52
DRD5 P21918 2/20 0.52
DRD3 P35462 2/20 0.52
RECQL P46063 2/20 0.52
SLC6A3 Q01959 2/20 0.52
APEX1 P27695 2/20 0.52
ALDH1A1 P00352 2/20 0.52
HTR1A P08908 2/20 0.52
ALOX15 P16050 2/20 0.52
PNMT P11086 1/20 0.52
TP53 P04637 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28735818 1.00 TAAR1 (0.52) TAAR1KDM4EADRA2ASLC6A2DRD2
SCHEMBL1469394 0.91 TAAR1 (0.56) TAAR1KDM4EADRA2ASLC6A2DRD2
Hydrochloric Acid SCHEMBL2385678 0.89 TAAR1 (0.54) TAAR1KDM4EADRA2ASLC6A2DRD2
SCHEMBL12345212 0.84 THRB (0.41) TAAR1KDM4EADRA2ASLC6A2DRD2
SCHEMBL17138365 0.84 TDP1 (0.62) TAAR1KDM4EADRA2ASLC6A2DRD2
SCHEMBL328576 0.84 TDP1 (0.62) TAAR1KDM4EADRA2ASLC6A2DRD2
Water SCHEMBL17686500 0.81 TDP1 (0.60) TAAR1KDM4EADRA2ASLC6A2DRD2
Hydrochloric Acid SCHEMBL3757551 0.81 TDP1 (0.64) TAAR1KDM4EADRA2ASLC6A2DRD2
Hydrochloric Acid SCHEMBL29134173 0.79 TDP1 (0.58) TAAR1KDM4EADRA2ASLC6A2DRD2
SCHEMBL13365218 0.77 ACHE (0.44) KDM4EADRA2ASLC6A2DRD1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109037689-B Preparation method of lithium ion silicon-based negative electrode material, battery negative electrode and lithium battery 亚士创能科技(上海)股份有限公司 2022-04-15 CN disclosed