Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331002 | 0.94 | SKP2 (0.50) | SKP2HTR2AGCGRTLR8CNR1 | |
| SCHEMBL45792 | 0.91 | SKP2 (0.50) | SKP2HTR2AGCGRTLR8SRC | |
| SCHEMBL28459291 | 0.89 | SKP2 (0.48) | SKP2HTR2ATLR8SRCESR1 | |
| SCHEMBL5567215 | 0.89 | SKP2 (0.48) | SKP2HTR2ATLR8SRCESR1 | |
| SCHEMBL31521779 | 0.89 | SKP2 (0.48) | SKP2HTR2ATLR8SRCESR1 | |
| SCHEMBL9516123 | 0.89 | SKP2 (0.48) | SKP2HTR2ATLR8SRCESR1 | |
| SCHEMBL294503 | 0.89 | SKP2 (0.48) | SKP2HTR2ATLR8SRCESR1 | |
| SCHEMBL1498860 | 0.89 | SKP2 (0.48) | SKP2HTR2ATLR8SRCESR1 | |
| SCHEMBL28248002 | 0.89 | SKP2 (0.48) | SKP2HTR2ATLR8SRCESR1 | |
| Hydrochloric Acid SCHEMBL28269844 | 0.87 | SKP2 (0.47) | SKP2HTR2ATLR8SRCESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247418-A1 | NAV1.7 BINDERS | Merck Sharp & Dohme LLC (US) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022109102-A1 | NAV1.7 BINDERS | MERCK SHARP & DOHME CORP. (US) | 2022-05-27 | — | — | WO | disclosed |
| WO-2015150822-A1 | MATERIALS AND METHODS FOR ANALYSING PHOSPHORYLATION OF A TARGET POLYPEPTIDE | THE UNIVERSITY OF BATH (GB) | 2015-10-08 | — | — | WO | disclosed |