SCHEMBL17142191

SCHEMBL17142191

CCCCCC(N)N(CC)c1ccc2c(=O)[nH][nH]c(=O)c2c1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.49
▸ TDP1 Q9NUW8 1/20 0.49
▸ AR P10275 7/20 0.37
▸ IGLV6-57 P01721 1/20 0.34
▸ PARP1 P09874 1/20 0.32
▸ PLA2G1B P04054 1/20 0.32
▸ PLA2G2A P14555 1/20 0.32
▸ GRK6 P43250 1/20 0.31
▸ DAO P14920 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17142184 0.99 KDM4E (0.51) KDM4ETDP1ARIGLV6-57PARP1
SCHEMBL17142228 0.96 KDM4E (0.50) KDM4ETDP1ARIGLV6-57PARP1
SCHEMBL5180879 0.91 KDM4E (0.50) KDM4ETDP1ARIGLV6-57GRK6
SCHEMBL17142193 0.85 KDM4E (0.50) KDM4ETDP1ARPARP1DAO
SCHEMBL17142227 0.81 KDM4E (0.54) KDM4ETDP1ARIGLV6-57GRK6
SCHEMBL12208991 0.74 KDM4E (0.78) KDM4ETDP1ARIGLV6-57GRK6
SCHEMBL9244286 0.73 KDM4E (0.67) KDM4ETDP1ARIGLV6-57GRK6
SCHEMBL5567066 0.72 KDM4E (0.75) KDM4ETDP1ARIGLV6-57GRK6
SCHEMBL6276512 0.68 KDM4E (0.39) KDM4ETDP1GRK6DAO
SCHEMBL437558 0.67 KDM4E (0.97) KDM4ETDP1ARIGLV6-57GRK6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3129783-B1 USE OF ABSORBENT PARTICLES FOR IMPROVING SIGNAL DETECTION IN AN ANALYSIS METHOD BIO RAD EUROPE GMBH (CH) 2021-06-02 — — EP disclosed
EP-3129782-B1 CONTROL MARKER FOR IMPLEMENTING METHODS OF ANALYSIS ON SPOTS BIO RAD EUROPE GMBH (CH) 2021-01-06 — — EP disclosed
EP-3129784-A1 USE OF A COLORANT IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD Bio-Rad Innovations (FR) 2017-02-15 — — EP disclosed
EP-3129782-A1 CONTROL MARKER FOR IMPLEMENTING ANALYSIS METHODS ON SPOTS Bio-Rad Innovations (FR) 2017-02-15 — — EP disclosed
EP-3129783-A1 USE OF ABSORBENT PARTICLES IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD Bio-Rad Innovations (FR) 2017-02-15 — — EP disclosed
EP-3126832-A1 CONTROL MEANS FOR IMPLEMENTING MULTIPLEX ANALYSIS METHODS Bio-Rad Innovations (FR) 2017-02-08 — — EP disclosed
WO-2015155255-A1 USE OF ABSORBENT PARTICLES IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD BIO-RAD INNOVATIONS (FR) 2015-10-15 — — WO disclosed
WO-2015155254-A1 CONTROL MARKER FOR IMPLEMENTING ANALYSIS METHODS ON SPOTS BIO-RAD INNOVATIONS (FR) 2015-10-15 — — WO disclosed
WO-2015155248-A1 USE OF A COLORANT IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD BIO-RAD INNOVATIONS (FR) 2015-10-15 — — WO disclosed
WO-2015150583-A1 CONTROL MEANS FOR IMPLEMENTING MULTIPLEX ANALYSIS METHODS BIO-RAD INNOVATIONS (FR) 2015-10-08 — — WO disclosed
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