Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 16/20 | 0.71 |
| ▸ | INSR | P06213 | 8/20 | 0.71 |
| ▸ | SRC | P12931 | 7/20 | 0.71 |
| ▸ | LYN | P07948 | 6/20 | 0.71 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.71 |
| ▸ | RET | P07949 | 3/20 | 0.71 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.71 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.71 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.71 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.71 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.71 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.71 |
| ▸ | LATS1 | O95835 | 1/20 | 0.71 |
| ▸ | YES1 | P07947 | 1/20 | 0.71 |
| ▸ | HCK | P08631 | 1/20 | 0.71 |
| ▸ | FECH | P22830 | 1/20 | 0.71 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.71 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.71 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.71 |
| ▸ | STK4 | Q13043 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171201 | 0.89 | IGF1R (0.71) | IGF1RINSRSRCLYNROCK2 | |
| SCHEMBL5936204 | 0.83 | IGF1R (0.97) | IGF1RINSRSRCLYNROCK2 | |
| Aew-541 SCHEMBL29358691 | 0.83 | IGF1R (1.00) | IGF1RINSRSRCLYNROCK2 | |
| SCHEMBL5936235 | 0.83 | IGF1R (0.97) | IGF1RINSRSRCLYNROCK2 | |
| SCHEMBL5936200 | 0.83 | IGF1R (0.97) | IGF1RINSRSRCLYNROCK2 | |
| SCHEMBL5936262 | 0.81 | IGF1R (1.00) | IGF1RINSRSRCLYNROCK2 | |
| SCHEMBL5936264 | 0.81 | IGF1R (1.00) | IGF1RINSRSRCLYNROCK2 | |
| SCHEMBL5936382 | 0.81 | IGF1R (1.00) | IGF1RINSRSRCLYNROCK2 | |
| SCHEMBL5936306 | 0.81 | IGF1R (0.98) | IGF1RINSRSRCLYNROCK2 | |
| SCHEMBL5936303 | 0.81 | IGF1R (0.98) | IGF1RINSRSRCLYNROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3125881-A1 | SUPRAMOLECULAR COMBINATORIAL THERAPEUTICS | Invictus Oncology Pvt. Ltd. (IN) | 2017-02-08 | — | — | EP | disclosed |
| WO-2015153345-A1 | SUPRAMOLECULAR COMBINATORIAL THERAPEUTICS | INVICTUS ONCOLOGY PVT. LTD. (IN) | 2015-10-08 | — | — | WO | disclosed |