Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 9/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 8/20 | 0.45 |
| ▸ | TUBB | P07437 | 8/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17145748 | 0.88 | MMP2 (0.44) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13778143 | 0.88 | CYP1A1 (0.46) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17145768 | 0.85 | CYP1A2 (0.49) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14414505 | 0.84 | CYP1A1 (0.47) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10030792 | 0.83 | TUBB1 (0.47) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13556713 | 0.81 | CYP1A1 (0.42) | TUBB1MMP2MMP9MMP8NFKB1 | |
| SCHEMBL17145756 | 0.81 | CYP1A1 (0.44) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17145732 | 0.81 | SRC (0.41) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17145733 | 0.81 | CYP1A1 (0.47) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17145753 | 0.81 | CYP1A1 (0.47) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE45907-E1 | Functionalized stilbene derivatives as improved vascular targeting agents | OXIGENE, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-RE45720-E1 | Functionalized stilbene derivatives as improved vascular targeting agents | OXIGENE, INC. (US) | 2015-10-06 | — | — | US | disclosed |