Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17058598 | 0.72 | GABRA1 (0.48) | GABRA1GABRB2HSP90AA1HSP90AB1 | |
| SCHEMBL8252287 | 0.68 | GABRA1 (0.54) | GABRA1GABRB2 | |
| SCHEMBL840750 | 0.67 | GABRA1 (0.64) | GABRA1GABRB2 | |
| SCHEMBL139640 | 0.67 | GABRA1 (0.52) | GABRA1GABRB2 | |
| SCHEMBL8091167 | 0.67 | GABRA1 (0.52) | GABRA1GABRB2 | |
| SCHEMBL18183963 | 0.67 | GABRA1 (0.47) | GABRA1GABRB2 | |
| SCHEMBL18089627 | 0.67 | GABRA1 (0.47) | GABRA1GABRB2 | |
| SCHEMBL23527437 | 0.66 | GABRA1 (0.62) | GABRA1GABRB2 | |
| SCHEMBL22781148 | 0.66 | GABRA1 (0.62) | GABRA1GABRB2 | |
| SCHEMBL2743774 | 0.66 | GABRA1 (0.62) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150516-B2 | Fluorination of organic compounds | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-10-06 | — | — | US | disclosed |