Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19229479 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTTDP1KMT2A | |
| SCHEMBL15761215 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTTDP1KMT2A | |
| SCHEMBL19229478 | 0.83 | KMT2A (0.43) | ALDH1A1KDM4EMAPTTDP1KMT2A | |
| SCHEMBL19229485 | 0.83 | TDP1 (0.44) | ALDH1A1KDM4EMAPTTDP1KMT2A | |
| SCHEMBL17146167 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTTDP1KMT2A | |
| SCHEMBL19229477 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTTDP1KMT2A | |
| SCHEMBL15761224 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTTDP1KMT2A | |
| SCHEMBL19229822 | 0.81 | HDAC3 (0.36) | ALDH1A1KDM4EMAPTKMT2ALMNA | |
| SCHEMBL19229834 | 0.79 | KDM4E (0.36) | ALDH1A1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL19229481 | 0.78 | CACNA1C (0.40) | ALDH1A1KDM4EMAPTTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725423-B2 | Tetrazolinone compound and applications thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-08 | — | — | US | disclosed |
| EP-2927218-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-10-07 | — | — | EP | disclosed |