Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29222540 | 0.81 | HCRTR2 (0.37) | MAPTHCRTR2APOBEC3AAPOBEC3GSCN9A | |
| SCHEMBL126557 | 0.81 | SERPINE1 (0.38) | — | |
| SCHEMBL26834 | 0.81 | SERPINE1 (0.38) | — | |
| SCHEMBL374062 | 0.81 | — | — | |
| SCHEMBL1138479 | 0.81 | SERPINE1 (0.38) | — | |
| SCHEMBL28199763 | 0.78 | MAPT (0.51) | ENPP2MAPTAPOBEC3AAPOBEC3GKDM4E | |
| Hydrochloric Acid SCHEMBL4395687 | 0.78 | — | — | |
| SCHEMBL26357095 | 0.78 | MAPT (0.37) | ENPP2MAPTHCRTR2APOBEC3AAPOBEC3G | |
| SCHEMBL21122754 | 0.76 | GPR35 (0.34) | MAPTHCRTR2GPR35 | |
| SCHEMBL12517730 | 0.76 | SCN9A (0.37) | MAPTHCRTR2APOBEC3AAPOBEC3GSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1220841-B1 | TRIFLUOROMETHYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2011-07-20 | — | — | EP | disclosed |
| EP-1220841-A2 | TRIFLUOROMETHYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | Bayer Aktiengesellschaft (DE) | 2002-07-10 | — | — | EP | disclosed |
| WO-2001023354-A2 | TRIFLUOROMETHYL-SUBSTITUTED SPIROCYCLIC KETOENOLS AND USE THEREOF AS PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-04-05 | — | — | WO | disclosed |