SCHEMBL17146994

SCHEMBL17146994

CCCCCCc1ccc2c3c(cccc13)C(=O)N(OS(=O)(=O)c1ccc(C)cc1)C2=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 8/20 0.58
▸ ALDH1A1 P00352 8/20 0.58
▸ HPGD P15428 5/20 0.58
▸ VDR P11473 2/20 0.56
▸ MAPT P10636 7/20 0.49
▸ F2 P00734 3/20 0.49
▸ KMT2A Q03164 6/20 0.48
▸ MEN1 O00255 3/20 0.48
▸ POLB P06746 1/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ LMNA P02545 1/20 0.45
▸ THRB P10828 1/20 0.45
▸ HTT P42858 2/20 0.45
▸ XBP1 P17861 1/20 0.41
▸ ELANE P08246 3/20 0.40
▸ NR1H2 P55055 1/20 0.40
▸ NR1H3 Q13133 1/20 0.40
▸ BRD1 O95696 2/20 0.39
▸ TAF1 P21675 2/20 0.39
▸ BRPF1 P55201 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17146983 1.00 KDM4E (0.58) KDM4EALDH1A1HPGDVDRMAPT
SCHEMBL17231427 0.96 KDM4E (0.61) KDM4EALDH1A1HPGDVDRMAPT
SCHEMBL17231436 0.88 KDM4E (0.67) KDM4EALDH1A1HPGDVDRMAPT
SCHEMBL17146964 0.85 ELANE (0.44) KDM4EALDH1A1MAPTKMT2AMEN1
SCHEMBL17231445 0.84 MAPT (0.47) KDM4EALDH1A1HPGDVDRMAPT
SCHEMBL17146980 0.84 KDM4E (0.53) KDM4EALDH1A1HPGDVDRMAPT
SCHEMBL23592283 0.81 ELANE (0.42) MAPTKMT2AMEN1POLBL3MBTL1
SCHEMBL17231431 0.81 ELANE (0.42) MAPTKMT2AMEN1POLBL3MBTL1
SCHEMBL17146973 0.81 ELANE (0.42) MAPTKMT2AMEN1POLBL3MBTL1
SCHEMBL21389580 0.81 ELANE (0.42) MAPTKMT2AMEN1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11754920-B2 Thermal acid generator and resist composition using same ADEKA CORPORATION (JP) 2023-09-12 — — US disclosed
US-11754920-B2 Thermal acid generator and resist composition using same ADEKA CORPORATION (JP) 2023-09-12 — — US disclosed
US-20220197136-A1 THERMAL ACID GENERATOR AND RESIST COMPOSITION USING SAME ADEKA CORPORATION (JP) 2022-06-23 — — US disclosed
US-20200183271-A1 THERMAL ACID GENERATOR AND RESIST COMPOSITION USING SAME ADEKA CORPORATION (JP) 2020-06-11 — — US disclosed
US-20190294044-A1 POSITIVE PHOTOSENSITIVE COMPOSITION, PATTERN USING SAME, AND METHOD OF MANUFACTURING PATTERN ADEKA CORPORATION (JP) 2019-09-26 — — US disclosed
US-20170182116-A1 SMAC Mimetic MEDIVIR AB (SE) 2017-06-29 — — US disclosed
US-20150315153-A1 NOVEL SULFONIC ACID DERIVATIVE COMPOUND, PHOTOACID GENERATOR, CATIONIC POLYMERIZATION INITIATOR, RESIST COMPOSITION, AND CATIONICALLY POLYMERIZABLE COMPOSITION ADEKA CORPORATION (JP) 2015-11-05 — — US disclosed
US-20150315153-A1 NOVEL SULFONIC ACID DERIVATIVE COMPOUND, PHOTOACID GENERATOR, CATIONIC POLYMERIZATION INITIATOR, RESIST COMPOSITION, AND CATIONICALLY POLYMERIZABLE COMPOSITION ADEKA CORPORATION (JP) 2015-11-05 — — US disclosed
EP-2927216-A1 NOVEL SULFONIC ACID DERIVATIVE COMPOUND, PHOTOACID GENERATOR, CATIONIC POLYMERIZATION INITIATOR, RESIST COMPOSITION, AND CATIONICALLY POLYMERIZABLE COMPOSITION Adeka Corporation (JP) 2015-10-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200183271-A1 THERMAL ACID GENERATOR AND RESIST COMPOSITION USING SAME ACSL1, GAR1, LRBA KDM4E 3952/4885ALDH1A1 39/4885HPGD 1875/4885
US-11754920-B2 Thermal acid generator and resist composition using same ACSL1, LRBA, GAR1 KDM4E 3767/4885ALDH1A1 40/4885HPGD 1949/4885
US-20170182116-A1 SMAC Mimetic SMARCC1, SMARCC2, MCL1 KDM4E 3002/4885ALDH1A1 4197/4885HPGD 4077/4885
US-20220197136-A1 THERMAL ACID GENERATOR AND RESIST COMPOSITION USING SAME ACSL1, LRBA, GAR1 KDM4E 3767/4885ALDH1A1 40/4885HPGD 1949/4885
US-20150315153-A1 NOVEL SULFONIC ACID DERIVATIVE COMPOUND, PHOTOACID GENERATOR, CATIONIC POLYMERIZATION INITIATOR, RESIST COMPOSITION, AND CATIONICALLY POLYMERIZABLE COMPOSITION ALAD, ARSA, AHR KDM4E 3039/4885ALDH1A1 355/4885HPGD 2805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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