Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10920075 | 0.98 | ACP3 (0.49) | ACP3CYP2D6AKR1C3AKR1C2PTGS1 | |
| SCHEMBL25515020 | 0.87 | ACP3 (0.49) | ACP3CYP2D6AKR1C3AKR1C2PTGS1 | |
| SCHEMBL10920070 | 0.83 | ACP3 (0.45) | ACP3AKR1C3AKR1C2SMN1; SMN2LMNA | |
| SCHEMBL29948859 | 0.82 | PTGS1 (0.61) | ACP3AKR1C3AKR1C2PTGS1SMN1; SMN2 | |
| SCHEMBL3240938 | 0.82 | PTGS1 (0.61) | ACP3AKR1C3AKR1C2PTGS1SMN1; SMN2 | |
| SCHEMBL1492650 | 0.82 | PTGS1 (0.61) | ACP3AKR1C3AKR1C2PTGS1SMN1; SMN2 | |
| SCHEMBL1651840 | 0.82 | PTGS1 (0.61) | ACP3AKR1C3AKR1C2PTGS1SMN1; SMN2 | |
| SCHEMBL28329651 | 0.82 | AKR1C3 (0.47) | CYP2D6AKR1C3AKR1C2PTGS2KDM4E | |
| SCHEMBL66944 | 0.81 | CYP2D6 (0.73) | CYP2D6AKR1C3AKR1C2PTGS2LMNA | |
| SCHEMBL5158960 | 0.81 | CYP2D6 (0.73) | CYP2D6AKR1C3AKR1C2PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334249-B2 | Inhibitors of cytomegalovirus | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-05-10 | — | — | US | disclosed |
| US-20150284348-A1 | INHIBITORS OF CYTOMEGALOVIRUS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284348-A1 | INHIBITORS OF CYTOMEGALOVIRUS | CDKN1A, CCNA1, IFNAR1 | ACP3 4425/4885CYP2D6 3355/4885AKR1C3 2128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.