SCHEMBL1492650

SCHEMBL1492650

Cc1cccc(C(C)C(=O)O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 9/20 0.61
PTGS2 P35354 9/20 0.61
MAPT P10636 3/20 0.61
SLC22A6 Q4U2R8 3/20 0.61
CXCR1 P25024 2/20 0.61
CXCR2 P25025 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
LMNA P02545 2/20 0.61
HPGD P15428 2/20 0.61
HIF1A Q16665 2/20 0.61
RECQL P46063 1/20 0.61
KDM4E B2RXH2 1/20 0.61
ALDH1A1 P00352 1/20 0.61
CYP3A4 P08684 1/20 0.61
MAPK1 P28482 1/20 0.61
PMP22 Q01453 1/20 0.61
HSD17B10 Q99714 1/20 0.61
CXCL8 P10145 1/20 0.61
THPO P40225 1/20 0.61
AKR1C3 P42330 6/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1651840 1.00 PTGS1 (0.61) PTGS1PTGS2MAPTSLC22A6CXCR1
SCHEMBL3240938 1.00 PTGS1 (0.61) PTGS1PTGS2MAPTSLC22A6CXCR1
SCHEMBL29948859 1.00 PTGS1 (0.61) PTGS1PTGS2MAPTSLC22A6CXCR1
SCHEMBL15695550 0.88 AKR1C3 (0.49) PTGS1PTGS2MAPTSLC22A6CXCR1
SCHEMBL20230822 0.88 AKR1C3 (0.49) PTGS1PTGS2MAPTSLC22A6CXCR1
SCHEMBL602096 0.87 PTGS2 (0.69) PTGS1PTGS2MAPTSLC22A6CXCR1
SCHEMBL10443244 0.85 ACP3 (0.49) PTGS1PTGS2MAPTSLC22A6CXCR1
SCHEMBL3053512 0.82 PARP1 (0.50) PTGS1PTGS2MAPTSLC22A6CXCR1
SCHEMBL2153144 0.82 ACP3 (0.46) PTGS1PTGS2MAPTSLC22A6CXCR1
SCHEMBL17147283 0.82 ACP3 (0.50) PTGS1PTGS2MAPTSLC22A6CXCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115872849-A Method for preparing 2, 5-dimethylphenylacetic acid 阜新睿光氟化学有限公司 2023-03-31 CN claimed
CN-110305010-B Preparation method of 2, 5-dimethylphenylacetic acid 江苏中旗科技股份有限公司 2022-05-13 CN claimed
WO-2025074305-A1 N-(1-(AMINOMETHYL)CYCLOPROPYL)(ARYL OR HETEROARYL) CARBOXAMIDE DERIVATIVES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-04-10 WO disclosed
CN-118666764-A Triazole amide compound, preparation method and application thereof 中国人民解放军海军军医大学 2024-09-20 CN disclosed
WO-2024010529-A1 PRODUCTION OF ENANTIOPURE ALCOHOLS, AMINES AND ACIDS FROM RACEMIC EPOXIDES BY CASCADE BIOTRANSFORMATION INVOLVING EPOXIDE ISOMERIZATION AND DYNAMIC KINETIC RESOLUTION NATIONAL UNIVERSITY OF SINGAPORE (SG) 2024-01-11 WO disclosed
US-20230111101-A1 PROCESS FOR THE PREPARATION OF A CHIRAL PROSTAGLANDIN ENOL INTERMEDIATE AND INTERMEDIATE COMPOUNDS USEFUL IN THE PROCESS EUROAPI HUNGARY LIMITED LIABILITY COMPANY (HU) 2023-04-13 US disclosed
CN-115872849-A Method for preparing 2, 5-dimethylphenylacetic acid 阜新睿光氟化学有限公司 2023-03-31 CN disclosed
CN-115872849-A Method for preparing 2, 5-dimethylphenylacetic acid 阜新睿光氟化学有限公司 2023-03-31 CN disclosed
CN-115485270-A Process for preparing chiral prostaglandin enol intermediates and intermediate compounds useful in the process 欧宜平匈牙利有限责任公司 2022-12-16 CN disclosed
EP-4100385-A1 REARRANGEMENT OF DIMETHYLPHENYLACYLATES USING ZEOLITES DSM IP Assets B.V. (NL) 2022-12-14 EP disclosed
EP-4077298-A1 PROCESS FOR THE PREPARATION OF A CHIRAL PROSTAGLANDIN ENOL INTERMEDIATE AND INTERMEDIATE COMPOUNDS USEFUL IN THE PROCESS EUROAPI Hungary Limited Liability Company (HU) 2022-10-26 EP disclosed
EP-1550662-A1 NOVEL ADENINE COMPOUND AND USE THEREOF SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2005-07-06 EP disclosed
WO-2005005393-A2 CCK-1 RECEPTOR MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2005-01-20 WO disclosed
US-6479693-B2 REACTING AN ETHENICALLY UNSATURATED COMPOUND SUCH AS STYRENE WITH AN ALCOHOL AND CARBON MONOXIDE IN ORGANIC SOLVENT USING WATER SOLUBLE PALLADIUM COMPLEX CATALYST TO OBTAIN SATURATED ALKOXYCARBONYLATED COMPOUND COUNCIL OF SCIENTIFIC AND INDUSTIAL RESEARCH (IN) 2002-11-12 US disclosed
US-20020137964-A1 Process for the preparation of a saturated carboxylic acid ester COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH 2002-09-26 US disclosed
EP-0386243-A1 PLATINUM (II) COMPLEXES SAGAMI CHEMICAL RESEARCH CENTER (JP) 1990-09-12 EP disclosed
US-4465855-A ANTIREUMATIC & ANTIINFLAMMATORIES CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) 1984-08-14 US disclosed
US-4385004-A Esters of ortho-allylphenol useful for the preparation of arylacetic acid derivatives CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1983-05-24 US disclosed
US-4317920-A ANTIRHEUMATIC AGENTS, ANTIINFLAMMATORY AGENTS CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1982-03-02 US disclosed
US-RE29981-E FROM FORMIC ESTERS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1979-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230111101-A1 PROCESS FOR THE PREPARATION OF A CHIRAL PROSTAGLANDIN ENOL INTERMEDIATE AND INTERMEDIATE COMPOUNDS USEFUL IN THE PROCESS PTGER1, PTGER4, PTGER2 PTGS1 9/4885PTGS2 19/4885MAPT 4689/4885
US-20020137964-A1 Process for the preparation of a saturated carboxylic acid ester ADH1C, ADH1A, ADH5 PTGS1 894/4885PTGS2 760/4885MAPT 3582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.