Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | HTR2B | P41595 | 4/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14945605 | 1.00 | HTR2C (0.58) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL13197434 | 0.90 | HTR2C (0.66) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL13197435 | 0.90 | HTR2C (0.66) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL25089783 | 0.88 | HTR2C (0.58) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL24065185 | 0.88 | HTR2C (0.58) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL24065187 | 0.88 | HTR2C (0.58) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL1065758 | 0.84 | HTR2C (0.77) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL19102563 | 0.81 | HTR2C (0.58) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL17147622 | 0.81 | HTR2C (0.58) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL17147616 | 0.80 | HTR2C (0.53) | HTR2CKDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422319-B2 | Bisaryl metallocenes and use thereof to produce polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| US-20150284418-A1 | BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS | BASELL POLYOLEFIN GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284418-A1 | BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS | PCBP1, PARG, PARN | HTR2C 3282/4885DRD2 3518/4885HTR2A 2670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.