Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 10/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 9/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17147672 | 1.00 | CHRM2 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL12252660 | 0.81 | — | — | |
| SCHEMBL10881613 | 0.77 | CHRM2 (0.53) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL17147621 | 0.77 | CHRM2 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL17147620 | 0.77 | CHRM2 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL19101156 | 0.77 | CHRM2 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL20869957 | 0.74 | CHRM2 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL16368642 | 0.74 | CHRM2 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL19101158 | 0.72 | CHRM2 (0.41) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL16446405 | 0.72 | CHRM2 (0.53) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422380-B2 | Non-bridged metallocene complexes for the polymerization of olefins | Basell Polyolefine Wesseling (DE) | 2016-08-23 | — | — | US | disclosed |
| US-9422319-B2 | Bisaryl metallocenes and use thereof to produce polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| US-20150284489-A1 | NON-BRIDGED METALLOCENE COMPLEXES FOR THE POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
| US-20150284418-A1 | BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS | BASELL POLYOLEFIN GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284418-A1 | BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS | PCBP1, PARG, PARN | CHRM2 3432/4885CHRM4 2885/4885CHRM5 3981/4885 |
| US-20150284489-A1 | NON-BRIDGED METALLOCENE COMPLEXES FOR THE POLYMERIZATION OF OLEFINS | PCBP1, MORF4L1, PPIL4 | CHRM2 4622/4885CHRM4 3719/4885CHRM5 4342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.