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Sugi Predict / Targets / MORF4L1

MORF4L1

Mortality factor 4-like protein 1 · Q9UBU8 · MORF4L1 on Sugi Atlas →

142 patent compounds predicted against MORF4L1, 85 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL19730381 SCHEMBL19730381 1.00 1/20
SCHEMBL27223881 SCHEMBL27223881 0.85 1/20
SCHEMBL29613516 SCHEMBL29613516 0.85 1/20
SCHEMBL24510772 SCHEMBL24510772 0.75 1/20
SCHEMBL29664786 SCHEMBL29664786 0.72 1/20
SCHEMBL24510615 SCHEMBL24510615 0.71 1/20
SCHEMBL24510649 SCHEMBL24510649 0.71 1/20
SCHEMBL29613411 SCHEMBL29613411 0.71 1/20
SCHEMBL27223857 SCHEMBL27223857 0.63 1/20
SCHEMBL29613449 SCHEMBL29613449 0.63 1/20
SCHEMBL399014 SCHEMBL399014 0.59 1/20
SCHEMBL911014 SCHEMBL911014 0.57 1/20
SCHEMBL30475010 SCHEMBL30475010 0.56 1/20
SCHEMBL12381279 SCHEMBL12381279 0.54 1/20
SCHEMBL30797925 SCHEMBL30797925 0.54 1/20
SCHEMBL24510651 SCHEMBL24510651 0.53 1/20
SCHEMBL3107714 SCHEMBL3107714 0.52 1/20
SCHEMBL13157828 SCHEMBL13157828 0.52 1/20
SCHEMBL4601494 SCHEMBL4601494 0.51 1/20
SCHEMBL16420772 SCHEMBL16420772 0.51 1/20

Clinical trials — most relevant to MORF4L1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Valproate and Levocarnitine in Children With Spinal Muscular Atrophy PHASE3UNKNOWN
Management of Retinitis Pigmentosa Via Combination of Wharton's Jelly-derived Mesenchymal Stem Cells and Magnovision PHASE3COMPLETED
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers PHASE2NOT_YET_RECRUITING
A Study of Sorafenib in Patients With Chemonaive Metastatic Uveal Melanoma PHASE2UNKNOWN
Human Leukocyte Antigen (HLA) - A*2402 Restricted Peptide Vaccine Therapy in Patients With Advanced Esophageal Cancer PHASE1COMPLETED
Mechanisms of Cell Death in Spinal Muscular Atrophy nanCOMPLETED
Genetic Determinants of Sudden Cardiac Death nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Pleiotropy and Mechanism of Peripheral Nerve Related Genes in the Progression of Amyotrophic Lateral Sclerosis nanUNKNOWN
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Mapping Novel Disease Genes for Dilated Cardiomyopathy nanCOMPLETED
CoMPaSS-NMD - Computational Models for New Patients Stratification Strategies of HNMD nanENROLLING_BY_INVITATION
Roles of Some Non-classic Biomarkers in Pediatric Pneumonia nanUNKNOWN
Identification of Genetic Variants Associated With Unexpected Infant Death Syndrome nanRECRUITING
Amyotrophic Lateral Sclerosis (ALS) Families Project nanRECRUITING
Melanocortin Gene Expression in Lymphocytes of Polymyalgia Patients nanCOMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Genetics of Familial and Sporadic ALS nanCOMPLETED
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma nanCOMPLETED
Cerebellar Mutism Syndrome Study nanRECRUITING
Genotype-Phenotype Associations in Pediatric Cardiomyopathy (PCM GENES) nanCOMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Selinexor (Nexpovio®) (SVd) in Patients With Relapsed or Refractory Multiple Myeloma nanACTIVE_NOT_RECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Collection of Blood Samples for DNA in Motor Neuron Disease nanCOMPLETED
Genetics of Cardiovascular and Neuromuscular Disease nanRECRUITING
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
Linkage Study in Familial Pulmonary Fibrosis nanCOMPLETED
PCD New Gene Discovery nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a MORF4L1 binder may also engage these)

ProteinNameSimilarity
P60762 — 1.000 P60762 →
Q5NVP9 — 0.977 Q5NVP9 →
Q6AYU1 — 0.977 Q6AYU1 →
A2A432 — 0.958 A2A432 →
Q6P5H6 — 0.952 Q6P5H6 →
Q9ERA0 — 0.951 Q9ERA0 →
RPTOR Regulatory-associated protein of mTOR 0.950 landscape →
Q62599 — 0.950 Q62599 →
X2JAU8 — 0.950 X2JAU8 →
MLX Max-like protein X 0.949 landscape →
Q8K4Q0 — 0.949 Q8K4Q0 →
Q6NRB5 — 0.949 Q6NRB5 →
Q9NPF5 — 0.949 Q9NPF5 →
Q8K4B0 — 0.949 Q8K4B0 →
Q6DN14 — 0.948 Q6DN14 →
G3V6U9 — 0.948 G3V6U9 →
Q9JI44 — 0.948 Q9JI44 →
E9PV86 — 0.947 E9PV86 →
Q13330 — 0.947 Q13330 →
A9X1D0 — 0.947 A9X1D0 →
B0VX69 — 0.947 B0VX69 →
Q503N9 — 0.946 Q503N9 →
USP47 Ubiquitin carboxyl-terminal hydrolase 47 0.946 landscape →
B5FW36 — 0.946 B5FW36 →
Q5ZML9 — 0.946 Q5ZML9 →
Q6NZH6 — 0.946 Q6NZH6 →
Q8BUL6 — 0.945 Q8BUL6 →
Q80YA3 — 0.945 Q80YA3 →
B1MTJ4 — 0.945 B1MTJ4 →
Q91WC0 — 0.945 Q91WC0 →