SCHEMBL17148015

SCHEMBL17148015

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nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 6/20 0.60
LGALS8 O00214 1/20 0.60
LGALS4 P56470 1/20 0.60
CD209 Q9NNX6 2/20 0.50
ENGASE Q8NFI3 1/20 0.49
MAPK1 P28482 2/20 0.48
CD69 Q07108 1/20 0.48
CHIA Q9BZP6 1/20 0.47
AMY2A P04746 2/20 0.47
LGALS1 P09382 1/20 0.47
LGALS7; LGALS7B P47929 1/20 0.47
ALDH1A1 P00352 1/20 0.44
THRB P10828 1/20 0.44
LGALS9 O00182 1/20 0.43
HPSE Q9Y251 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29370786 1.00 LGALS3 (0.60) LGALS3LGALS8LGALS4CD209ENGASE
SCHEMBL17148009 1.00 LGALS3 (0.60) LGALS3LGALS8LGALS4CD209ENGASE
SCHEMBL29540408 1.00 LGALS3 (0.60) LGALS3LGALS8LGALS4CD209ENGASE
SCHEMBL30110520 1.00 LGALS3 (0.60) LGALS3LGALS8LGALS4CD209ENGASE
SCHEMBL29419069 1.00 LGALS3 (0.60) LGALS3LGALS8LGALS4CD209ENGASE
SCHEMBL29694256 0.98 LGALS3 (0.59) LGALS3LGALS8LGALS4CD209ENGASE
SCHEMBL29370195 0.97 LGALS3 (0.57) LGALS3LGALS8LGALS4CD209ENGASE
SCHEMBL29532287 0.97 LGALS3 (0.61) LGALS3LGALS8LGALS4CD209ENGASE
SCHEMBL31154034 0.96 LGALS3 (0.56) LGALS3LGALS8LGALS4CD209ENGASE
SCHEMBL30943987 0.96 LGALS3 (0.56) LGALS3LGALS8LGALS4CD209ENGASE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150283227-A1 SYNTHETIC ENV PROTEINS DANA-FARBER CANCER INSTITUTE 2015-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150283227-A1 SYNTHETIC ENV PROTEINS CD4, EEA1, FURIN LGALS3 150/4885LGALS8 170/4885LGALS4 157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.