SCHEMBL171487

SCHEMBL171487

FCc1ccc(CS)cc1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 6/20 0.60
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127369 0.83 IDO1 (0.69) IDO1HRH3
SCHEMBL1338455 0.83 HRH3 (0.35) IDO1HRH3
SCHEMBL328579 0.75
SCHEMBL441314 0.75
SCHEMBL441726 0.73 IDO1 (0.58) IDO1HRH3
SCHEMBL17756329 0.73 IDO1 (0.58) IDO1HRH3
SCHEMBL635341 0.73 IDO1 (0.58) IDO1
SCHEMBL9552726 0.73 HRH3 (0.47) IDO1HRH3
SCHEMBL9510277 0.73 HRH3 (0.47) IDO1HRH3
SCHEMBL9552515 0.73 GFER (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2426130-A1 PURINE DERIVATIVE AND ANTITUMOR AGENT USING SAME ZENYAKU KOGYO KABUSHIKIKAISHA (JP) 2012-03-07 EP disclosed