Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714226 | 0.91 | PTGDR2 (0.60) | PTGDR2KDM4EALDH1A1PKMMEN1 | |
| SCHEMBL27852039 | 0.91 | PTGDR2 (0.60) | PTGDR2LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1713882 | 0.88 | PTGDR2 (0.57) | PTGDR2SMN1; SMN2KDM4EALDH1A1PKM | |
| SCHEMBL1713709 | 0.86 | PTGDR2 (0.83) | PTGDR2LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5200959 | 0.83 | PTGDR2 (0.59) | PTGDR2KDM4EALDH1A1PKMMEN1 | |
| SCHEMBL27852040 | 0.82 | PTGDR2 (0.59) | PTGDR2LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL27852058 | 0.81 | PTGDR2 (0.58) | PTGDR2KDM4EALDH1A1PKMMEN1 | |
| SCHEMBL5198743 | 0.81 | MEN1 (0.41) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3939170 | 0.79 | PTGDR2 (0.61) | PTGDR2LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1714400 | 0.79 | PTGDR2 (0.90) | PTGDR2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817282-B1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2011-07-20 | — | — | EP | disclosed |