Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.59 |
| ▸ | FNTA | P49354 | 10/20 | 0.55 |
| ▸ | FNTB | P49356 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27833957 | 0.91 | PTGDR2 (0.57) | PTGDR2FNTAFNTBKDM4EALDH1A1 | |
| SCHEMBL1713822 | 0.86 | PTGDR2 (0.80) | PTGDR2FNTAFNTBKDM4EALDH1A1 | |
| SCHEMBL27693175 | 0.84 | FNTA (0.61) | PTGDR2FNTAFNTBKDM4EALDH1A1 | |
| SCHEMBL1714674 | 0.83 | PTGDR2 (0.60) | PTGDR2KDM4EALDH1A1PKMKMT2A | |
| SCHEMBL1714922 | 0.83 | PTGDR2 (0.61) | PTGDR2KDM4EALDH1A1PKMMEN1 | |
| SCHEMBL27852039 | 0.82 | PTGDR2 (0.60) | PTGDR2KDM4EALDH1A1PKMMEN1 | |
| SCHEMBL1714226 | 0.82 | PTGDR2 (0.60) | PTGDR2KDM4EALDH1A1PKMMEN1 | |
| SCHEMBL1713882 | 0.80 | PTGDR2 (0.57) | PTGDR2KDM4EALDH1A1PKMMEN1 | |
| SCHEMBL27852040 | 0.74 | PTGDR2 (0.59) | PTGDR2KDM4EALDH1A1PKMMEN1 | |
| SCHEMBL1713552 | 0.74 | PTGDR2 (0.78) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101107226-B | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB | 2012-01-18 | — | — | CN | claimed |
| EP-1817282-A1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | AstraZeneca AB (SE) | 2007-08-15 | — | — | EP | claimed |
| WO-2006056752-A1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2006-06-01 | — | — | WO | claimed |
| CN-101107226-B | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB | 2012-01-18 | — | — | CN | disclosed |