Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 16/20 | 0.59 |
| ▸ | AGXT | P21549 | 10/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1715405 | 0.98 | IDO1 (0.60) | IDO1AGXTCYP3A4 | |
| SCHEMBL28780545 | 0.83 | TSHR (0.47) | — | |
| SCHEMBL513287 | 0.79 | ALDH1A1 (0.45) | — | |
| SCHEMBL513288 | 0.79 | GRIN2B (0.50) | — | |
| SCHEMBL13141037 | 0.79 | IDO1 (0.61) | IDO1AGXTCYP3A4 | |
| SCHEMBL106741 | 0.78 | HTR2C (0.54) | — | |
| SCHEMBL2092054 | 0.78 | SLC6A4 (0.56) | — | |
| SCHEMBL290512 | 0.78 | ALDH1A1 (0.44) | — | |
| SCHEMBL5921896 | 0.77 | MAOB (0.70) | — | |
| SCHEMBL1715046 | 0.77 | IDO1 (0.61) | IDO1AGXTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244117-A1 | Novel Hydroxamic Acid Esters and Pharmaceutical Use Thereof | LEO PHARMA A/S (DK) | 2007-10-18 | — | — | US | claimed |
| CN-1906155-A | Novel hydroxamic acid esters and pharmaceutical use thereof | LEO PHARMA AS (DK) | 2007-01-31 | — | — | CN | claimed |
| US-20040248313-A1 | Process for production of collection columns for carbonyl compounds | SUMITOMO CHEMICAL ANALYSIS SERVICE, LTD. (JP) | 2004-12-09 | — | — | US | claimed |
| EP-1431760-A1 | PROCESS FOR PRODUCTION OF COLLECTION COLUMNS FOR CARBONYL COMPOUNDS | SUMIKA CHEMICAL ANALYSIS SERVICE, LTD. (JP) | 2004-06-23 | — | — | EP | claimed |
| US-8034811-B2 | Hydroxamic acid esters and pharmaceutical use thereof | LEO PHARMA A/S (DK) | 2011-10-11 | — | — | US | disclosed |
| US-8034811-B2 | Hydroxamic acid esters and pharmaceutical use thereof | LEO PHARMA A/S (DK) | 2011-10-11 | — | — | US | disclosed |
| US-8034811-B2 | Hydroxamic acid esters and pharmaceutical use thereof | LEO PHARMA A/S (DK) | 2011-10-11 | — | — | US | disclosed |
| EP-1697312-B1 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA AS (DK) | 2011-07-20 | — | — | EP | disclosed |
| EP-1697312-B1 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA AS (DK) | 2011-07-20 | — | — | EP | disclosed |
| CN-1906155-B | Novel hydroxamic acid ester derivant and pharmaceutical use thereof | LEO PHARMA AS | 2010-06-23 | — | — | CN | disclosed |
| US-20070244117-A1 | Novel Hydroxamic Acid Esters and Pharmaceutical Use Thereof | LEO PHARMA A/S (DK) | 2007-10-18 | — | — | US | disclosed |
| US-20070244117-A1 | Novel Hydroxamic Acid Esters and Pharmaceutical Use Thereof | LEO PHARMA A/S (DK) | 2007-10-18 | — | — | US | disclosed |
| US-20070244117-A1 | Novel Hydroxamic Acid Esters and Pharmaceutical Use Thereof | LEO PHARMA A/S (DK) | 2007-10-18 | — | — | US | disclosed |
| CN-1906155-A | Novel hydroxamic acid esters and pharmaceutical use thereof | LEO PHARMA AS (DK) | 2007-01-31 | — | — | CN | disclosed |
| WO-2006037496-A1 | POLYHALOGENATED PROPENE BENZOQUINONE DIOXIME DERIVATIVES AND ITS USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2006-04-13 | — | — | WO | disclosed |
| US-20040248313-A1 | Process for production of collection columns for carbonyl compounds | SUMITOMO CHEMICAL ANALYSIS SERVICE, LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-1431760-A1 | PROCESS FOR PRODUCTION OF COLLECTION COLUMNS FOR CARBONYL COMPOUNDS | SUMIKA CHEMICAL ANALYSIS SERVICE, LTD. (JP) | 2004-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244117-A1 | Novel Hydroxamic Acid Esters and Pharmaceutical Use Thereof | F9, F12, HDAC9 | IDO1 3029/4885AGXT 131/4885CYP3A4 3344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.