Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | CTSK | P43235 | 8/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17079742 | 0.94 | MEN1 (0.72) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL26520283 | 0.94 | MEN1 (0.72) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL25501121 | 0.92 | MEN1 (0.79) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL25090844 | 0.88 | MEN1 (0.88) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL15376152 | 0.87 | MEN1 (0.71) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL12341083 | 0.87 | MEN1 (0.71) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL6200619 | 0.86 | MEN1 (0.64) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL6200616 | 0.86 | MEN1 (0.64) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL28079376 | 0.84 | MEN1 (0.71) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL27594927 | 0.84 | MEN1 (0.71) | MEN1GAAKMT2ACTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015154039-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2015-10-08 | — | — | WO | disclosed |