Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET3 | O43151 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | FBXL19 | Q6PCT2 | 7/20 | 0.43 |
| ▸ | CXXC5 | Q7LFL8 | 7/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 7/20 | 0.43 |
| ▸ | CXXC4 | Q9H2H0 | 7/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 7/20 | 0.43 |
| ▸ | TET1 | Q8NFU7 | 5/20 | 0.43 |
| ▸ | BTK | Q06187 | 13/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16380338 | 0.82 | KMT2A (0.43) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL19054828 | 0.80 | KMT2A (0.44) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL16375283 | 0.78 | KMT2A (0.40) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL15472505 | 0.78 | KMT2A (0.40) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL19352905 | 0.78 | KMT2A (0.40) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL24244473 | 0.78 | KMT2A (0.41) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL9993085 | 0.77 | HRH3 (0.32) | — | |
| SCHEMBL29829152 | 0.77 | KMT2A (0.47) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL12163604 | 0.75 | TEAD1 (0.42) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL20849781 | 0.75 | TET3 (0.45) | TET3KMT2AFBXL19CXXC5KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015151006-A1 | SUBSTITUTED PURINE COMPOUNDS AS BTK INHIBITORS | LUPIN LIMITED (IN) | 2015-10-08 | — | — | WO | disclosed |