Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1831524 | 0.80 | PRMT3 (0.44) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL12022327 | 0.80 | PRMT3 (0.44) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL3318828 | 0.80 | PRMT3 (0.44) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL24225246 | 0.80 | PRMT3 (0.44) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL10013647 | 0.78 | PRMT3 (0.42) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL22123554 | 0.78 | PRMT3 (0.42) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL21381233 | 0.77 | PRMT3 (0.41) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL23732850 | 0.77 | PRMT3 (0.41) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL1834258 | 0.77 | PRMT3 (0.41) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL27467974 | 0.77 | PRMT3 (0.50) | PRMT3CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015154039-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2015-10-08 | — | — | WO | disclosed |