Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.32 |
| ▸ | CCNK | O75909 | 2/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CDK7 | P50613 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | CCNH | P51946 | 2/20 | 0.32 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17150744 | 0.89 | CCNT1 (0.33) | CCNT1CCNKCCNE1CDK2CDK7 | |
| SCHEMBL17150641 | 0.82 | CDK2 (0.38) | CCNT1CCNKCCNE1CDK2CDK7 | |
| SCHEMBL17141323 | 0.80 | CCNT1 (0.34) | CCNT1CCNKCCNE1CDK2CDK7 | |
| SCHEMBL20412364 | 0.76 | CDK2 (0.34) | CCNT1CCNKCCNE1CDK2CDK7 | |
| SCHEMBL17150724 | 0.76 | CDK7 (0.50) | CCNT1CCNKCDK2CDK7CDK9 | |
| SCHEMBL17150740 | 0.71 | CDK2 (0.39) | CCNT1CCNKCDK2CDK7CDK9 | |
| SCHEMBL17150639 | 0.69 | CDK2 (0.35) | CCNT1CCNKCCNE1CDK2CDK7 | |
| SCHEMBL17150455 | 0.67 | CDK7 (0.56) | CCNT1CCNKCCNE1CDK2CDK7 | |
| SCHEMBL20416030 | 0.66 | CCNA2 (0.33) | CDK2 | |
| SCHEMBL20416033 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015154038-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2015-10-08 | — | — | WO | disclosed |