Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 14/20 | 0.33 |
| ▸ | CDK2 | P24941 | 14/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 14/20 | 0.33 |
| ▸ | AURKA | O14965 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20416035 | 0.83 | CCNA2 (0.32) | CCNA2CDK2CCNA1AURKA | |
| SCHEMBL20416033 | 0.83 | — | — | |
| SCHEMBL17150641 | 0.81 | CDK2 (0.38) | CCNA2CDK2CCNA1 | |
| SCHEMBL20416031 | 0.78 | CDK7 (0.45) | CCNA2CDK2 | |
| SCHEMBL20416032 | 0.78 | CDK7 (0.45) | CCNA2CDK2 | |
| SCHEMBL21026880 | 0.77 | ALOX5AP (0.34) | — | |
| SCHEMBL20416029 | 0.71 | CDK7 (0.42) | CDK2 | |
| SCHEMBL20416347 | 0.71 | CDK7 (0.42) | CDK2 | |
| SCHEMBL17141323 | 0.68 | CCNT1 (0.34) | CDK2 | |
| SCHEMBL20412364 | 0.67 | CDK2 (0.34) | CCNA2CDK2CCNA1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180208578-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208578-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | CDK7, CDK3, CDK9 | CCNA2 38/4885CDK2 7/4885CCNA1 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.