Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.78 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.78 |
| ▸ | ESR1 | P03372 | 18/20 | 0.76 |
| ▸ | ESR2 | Q92731 | 14/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2811903 | 0.92 | EBP (0.88) | EBPSIGMAR1ESR1ESR2 | |
| SCHEMBL2817373 | 0.91 | EBP (0.86) | EBPSIGMAR1ESR1ESR2 | |
| SCHEMBL13350303 | 0.91 | EBP (0.86) | EBPSIGMAR1ESR1ESR2 | |
| SCHEMBL2811811 | 0.91 | EBP (0.86) | EBPSIGMAR1ESR1ESR2 | |
| SCHEMBL20387891 | 0.88 | EBP (0.79) | EBPSIGMAR1ESR1ESR2 | |
| Nafoxidine SCHEMBL153125 | 0.88 | EBP (1.00) | EBPSIGMAR1ESR1ESR2 | |
| Nafoxidine SCHEMBL10563464 | 0.88 | EBP (1.00) | EBPSIGMAR1ESR1ESR2 | |
| Nafoxidine SCHEMBL29494604 | 0.88 | EBP (1.00) | EBPSIGMAR1ESR1ESR2 | |
| SCHEMBL10025771 | 0.88 | EBP (0.81) | EBPSIGMAR1ESR1ESR2 | |
| Nafoxidine SCHEMBL29562423 | 0.87 | EBP (0.98) | EBPSIGMAR1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9687458-B2 | Trans-clomiphene for use in cancer therapy | REPROS THERAPEUTICS INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-20150283099-A1 | Trans-Clomiphene for Use in Cancer Therapy | REPROS THERAPEUTICS INC. (US) | 2015-10-08 | — | — | US | disclosed |