Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 8/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | KDM1A | O60341 | 1/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | RAD52 | P43351 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.58 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.58 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17154375 | 0.87 | KMT2A (0.66) | KMT2AKDM4EMEN1MAPTNPC1 | |
| SCHEMBL4159315 | 0.87 | KDM4E (0.66) | KMT2AKDM4EMEN1MAPTNPC1 | |
| SCHEMBL2374293 | 0.81 | MAPT (1.00) | KMT2AKDM4EMEN1MAPTNPC1 | |
| SCHEMBL17154362 | 0.80 | KDM1A (0.74) | KMT2AKDM4EMEN1MAPTNPC1 | |
| SCHEMBL4163695 | 0.78 | KDM4E (0.65) | KMT2AKDM4EMEN1MAPTNPC1 | |
| SCHEMBL4163110 | 0.78 | KMT2A (0.66) | KMT2AKDM4EMEN1MAPTNPC1 | |
| SCHEMBL6080450 | 0.76 | KDM4E (0.51) | KMT2AKDM4EMEN1MAPTNPC1 | |
| SCHEMBL29226582 | 0.76 | KMT2A (0.68) | KMT2AKDM4EMEN1MAPTNPC1 | |
| SCHEMBL17154400 | 0.76 | KDM1A (1.00) | KMT2AKDM4EMEN1MAPTSMN1; SMN2 | |
| SCHEMBL3776520 | 0.76 | KMT2A (0.65) | KMT2AKDM4EMEN1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015153535-A1 | NOVEL HDMX INHIBITORS AND THEIR USE FOR CANCER TREATMENT | MiRx Pharmaceuticals, LLC (US) | 2015-10-08 | — | — | WO | disclosed |