Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 1.00 |
| ▸ | NPC1 | O15118 | 8/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | RAB9A | P51151 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | PABPC1 | P11940 | 1/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.69 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.69 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.69 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.69 |
| ▸ | CBFB | Q13951 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.66 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.59 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24999593 | 0.88 | MAPT (0.78) | MAPTNPC1KDM4ERAB9AKMT2A | |
| SCHEMBL9613366 | 0.86 | KDM4E (0.75) | MAPTNPC1KDM4ERAB9AKMT2A | |
| SCHEMBL9613310 | 0.85 | KDM4E (0.74) | MAPTNPC1KDM4ERAB9AKMT2A | |
| SCHEMBL18075701 | 0.81 | KDM4E (1.00) | MAPTNPC1KDM4ERAB9AKMT2A | |
| SCHEMBL12311048 | 0.81 | RAB9A (0.69) | MAPTNPC1KDM4ERAB9AKMT2A | |
| SCHEMBL17154455 | 0.81 | KMT2A (0.68) | MAPTNPC1KDM4ERAB9AKMT2A | |
| SCHEMBL28793880 | 0.81 | KDM4E (0.68) | MAPTNPC1KDM4ERAB9AKMT2A | |
| SCHEMBL17154375 | 0.80 | KMT2A (0.66) | MAPTNPC1KDM4ERAB9AKMT2A | |
| SCHEMBL4163110 | 0.80 | KMT2A (0.66) | MAPTNPC1KDM4ERAB9AKMT2A | |
| SCHEMBL4159315 | 0.80 | KDM4E (0.66) | MAPTNPC1KDM4ERAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119798-A1 | METHODS FOR REDUCING SUPEROXIDE ANIONS IN EUKARYOTIC ORGANISMS | HEALTH RESEARCH, INC. (US) | 2011-09-29 | — | — | WO | disclosed |