Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 15/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAD52 | P43351 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17154456 | 0.86 | KDM1A (0.70) | KDM1APOLBRAD52KMT2AKDM4E | |
| SCHEMBL4933340 | 0.80 | KDM1A (0.57) | KDM1APOLBRAD52KMT2AKDM4E | |
| SCHEMBL17154429 | 0.76 | KDM1A (0.64) | KDM1APOLBRAD52KMT2AKDM4E | |
| SCHEMBL17154413 | 0.75 | KDM1A (0.71) | KDM1APOLBRAD52KMT2AKDM4E | |
| SCHEMBL3347553 | 0.75 | KDM1A (1.00) | KDM1A | |
| SCHEMBL4941215 | 0.74 | KMT2A (0.61) | KDM1APOLBRAD52KMT2AKDM4E | |
| SCHEMBL902770 | 0.74 | KDM1A (1.00) | KDM1APOLBRAD52KMT2AKDM4E | |
| SCHEMBL17423211 | 0.73 | KDM1A (0.75) | KDM1APOLBRAD52KMT2AKDM4E | |
| SCHEMBL15673265 | 0.73 | KDM1A (0.75) | KDM1APOLBRAD52KMT2AGFER | |
| SCHEMBL4939506 | 0.73 | KDM1A (0.75) | KDM1APOLBRAD52KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015153535-A1 | NOVEL HDMX INHIBITORS AND THEIR USE FOR CANCER TREATMENT | MiRx Pharmaceuticals, LLC (US) | 2015-10-08 | — | — | WO | disclosed |