SCHEMBL17154708

SCHEMBL17154708

c1ccc(-c2ccc(-c3ccc(-c4ccc5[nH]c6ccc(-c7ccc(-c8ccc(-c9ccccc9)cc8)cc7)cc6c5c4)cc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 2/20 0.57
CCND1 P24385 2/20 0.57
JAK2 O60674 2/20 0.55
MKNK1 Q9BUB5 1/20 0.50
AHR P35869 1/20 0.50
NPC1 O15118 1/20 0.50
GABRA1 P14867 2/20 0.49
GABRG2 P18507 2/20 0.49
GABRB3 P28472 2/20 0.49
GABRA5 P31644 2/20 0.49
GABRA3 P34903 2/20 0.49
GABRA2 P47869 2/20 0.49
GABRA6 Q16445 2/20 0.49
TNKS2 Q9H2K2 1/20 0.47
DYRK3 O43781 1/20 0.47
CLK1 P49759 1/20 0.47
CLK2 P49760 1/20 0.47
CLK3 P49761 1/20 0.47
GSK3B P49841 1/20 0.47
CDK5 Q00535 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL149685 1.00 CDK4 (0.57) CDK4CCND1JAK2MKNK1AHR
SCHEMBL12001022 1.00 CDK4 (0.57) CDK4CCND1JAK2MKNK1AHR
SCHEMBL29386403 1.00 CDK4 (0.57) CDK4CCND1JAK2MKNK1AHR
SCHEMBL30300831 1.00 CDK4 (0.57) CDK4CCND1JAK2MKNK1AHR
SCHEMBL19041639 1.00 CDK4 (0.57) CDK4CCND1JAK2MKNK1AHR
SCHEMBL3365890 1.00 CDK4 (0.57) CDK4CCND1JAK2MKNK1AHR
Ammonia Solution, Strong SCHEMBL25177144 0.98 CDK4 (0.56) CDK4CCND1JAK2MKNK1AHR
SCHEMBL3365443 0.96 CDK4 (0.54) CDK4CCND1JAK2MKNK1AHR
SCHEMBL14929461 0.96 CDK4 (0.54) CDK4CCND1JAK2MKNK1AHR
SCHEMBL20232184 0.96 CDK4 (0.54) CDK4CCND1JAK2MKNK1AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015152547-A1 NOVEL COMPOUND AND LIGHT EMITTING ELEMENT COMPRISING SAME 주식회사 엘엠에스 2015-10-08 WO disclosed