SCHEMBL149685

SCHEMBL149685

c1ccc(-c2ccc3[nH]c4ccc(-c5ccccc5)cc4c3c2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 2/20 0.57
CCND1 P24385 2/20 0.57
JAK2 O60674 2/20 0.55
MKNK1 Q9BUB5 1/20 0.50
AHR P35869 1/20 0.50
NPC1 O15118 1/20 0.50
GABRA1 P14867 2/20 0.49
GABRG2 P18507 2/20 0.49
GABRB3 P28472 2/20 0.49
GABRA5 P31644 2/20 0.49
GABRA3 P34903 2/20 0.49
GABRA2 P47869 2/20 0.49
GABRA6 Q16445 2/20 0.49
TNKS2 Q9H2K2 1/20 0.47
DYRK3 O43781 1/20 0.47
CLK1 P49759 1/20 0.47
CLK2 P49760 1/20 0.47
CLK3 P49761 1/20 0.47
GSK3B P49841 1/20 0.47
CDK5 Q00535 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12001022 1.00 CDK4 (0.57) CDK4CCND1JAK2MKNK1AHR
SCHEMBL29386403 1.00 CDK4 (0.57) CDK4CCND1JAK2MKNK1AHR
SCHEMBL30300831 1.00 CDK4 (0.57) CDK4CCND1JAK2MKNK1AHR
SCHEMBL19041639 1.00 CDK4 (0.57) CDK4CCND1JAK2MKNK1AHR
SCHEMBL17154708 1.00 CDK4 (0.57) CDK4CCND1JAK2MKNK1AHR
SCHEMBL3365890 1.00 CDK4 (0.57) CDK4CCND1JAK2MKNK1AHR
Ammonia Solution, Strong SCHEMBL25177144 0.98 CDK4 (0.56) CDK4CCND1JAK2MKNK1AHR
SCHEMBL3365443 0.96 CDK4 (0.54) CDK4CCND1JAK2MKNK1AHR
SCHEMBL14929461 0.96 CDK4 (0.54) CDK4CCND1JAK2MKNK1AHR
SCHEMBL20232184 0.96 CDK4 (0.54) CDK4CCND1JAK2MKNK1AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1519 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114716476-B Carbazole derivative-based self-assembled monolayer hole transport material and synthesis method and application thereof 嘉兴学院 2024-05-03 CN claimed
CN-116283989-B Trans-quinacridone compound and preparation method and application thereof 华南理工大学 2024-03-01 CN claimed
CN-117402102-A Diamine containing carbazole moieties and polyimide gas separation membrane prepared from diamine and method 西北工业大学 2024-01-16 CN claimed
CN-114478599-B Boron-containing organic fluorescent molecule and preparation method and application thereof 南京工业大学 2023-10-13 CN claimed
CN-116874529-A Self-assembled monolayer hole transport material based on alkyl polyphosphoric acid anchoring group, and synthesis method and application thereof 嘉兴学院 2023-10-13 CN claimed
EP-4025643-B1 THERMOPLASTIC MOLDING COMPOSITIONS THAT RESIST HEAT BASF SE (DE) 2023-08-16 EP claimed
CN-115433343-A Epoxy resin based ultra-long organic room temperature phosphorescent material and preparation method and application thereof 深圳先进电子材料国际创新研究院 2022-12-06 CN claimed
CN-115404071-A Organic room-temperature phosphorescent cross-linked composite film, preparation method and application 华南理工大学 2022-11-29 CN claimed
CN-115355819-A Method for qualitatively comparing free volume of different epoxy resin condensate 深圳先进电子材料国际创新研究院 2022-11-18 CN claimed
US-20220315738-A1 THERMOPLASTIC MOLDING COMPOSITIONS THAT RESIST HEAT BASF SE (DE) 2022-10-06 US claimed
CN-113372261-A Method for preparing 1-bromine/chlorocarbazole and derivatives thereof 中国科学院兰州化学物理研究所 2021-09-10 CN claimed
CN-112876406-A Deuterated carbazole compound, preparation method thereof, photoelectric material and medicine 安徽秀朗新材料科技有限公司 2021-06-01 CN claimed
CN-110950846-A Benzimidazole bipyrimidine derivative and application thereof 西安瑞联新材料股份有限公司 2020-04-03 CN claimed
CN-110105812-A A kind of no ink ink-jet ink and its preparation method and application 重庆理工大学 2019-08-09 CN claimed
CN-107778212-A One kind 1,5 2 substitutes naphthalene derivatives and its application 北京鼎材科技有限公司 2018-03-09 CN claimed
CN-107778213-A One kind 1,4 2 substitutes naphthalene derivatives and application 北京鼎材科技有限公司 2018-03-09 CN claimed
CN-107629785-A A kind of asymmetrical type hot activation delayed fluorescence material and its synthetic method and application 华南师范大学 2018-01-26 CN claimed
US-7745988-B2 3, 6-diphenylcarbazole compound and organic electroluminescent device RICOH COMPANY, LIMITED (JP) 2010-06-29 US claimed
EP-1237887-B1 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS SERONO LAB (CH) 2008-06-04 EP claimed
US-20050084711-A1 3, 6-Diphenylcarbazole compound and organic electroluminescent device RICOH COMPANY LIMITED (JP) 2005-04-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050084711-A1 3, 6-Diphenylcarbazole compound and organic electroluminescent device OXA1L, MCU, SLC25A21 CDK4 465/4885CCND1 1915/4885JAK2 2826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.