Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17154885 | 0.87 | DHODH (0.47) | AURKAKDM4EATMFABP3FABP4 | |
| SCHEMBL15401372 | 0.82 | FABP3 (0.46) | AURKAKDM4EATMFABP3FABP4 | |
| Benzene SCHEMBL28417037 | 0.81 | FABP4 (0.55) | AURKAKDM4EATMFABP3FABP4 | |
| SCHEMBL29372518 | 0.81 | FABP4 (0.55) | AURKAKDM4EATMFABP3FABP4 | |
| SCHEMBL17699104 | 0.81 | FABP4 (0.55) | AURKAKDM4EATMFABP3FABP4 | |
| SCHEMBL588648 | 0.81 | FABP4 (0.55) | AURKAKDM4EATMFABP3FABP4 | |
| SCHEMBL2037022 | 0.81 | DHODH (0.57) | AURKAKDM4EATMDHODHALDH1A1 | |
| SCHEMBL17154876 | 0.77 | FABP4 (0.56) | AURKAKDM4EATMFABP3FABP4 | |
| SCHEMBL17503363 | 0.77 | EPHX2 (0.51) | KDM4EDHODHALDH1A1TSHRALOX15 | |
| SCHEMBL17733477 | 0.77 | FABP4 (0.52) | AURKAKDM4EATMFABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3126371-B1 | METAL COMPLEXES, COMPRISING CARBENE LIGANDS HAVING AN O-SUBSTITUTED NON-CYCLOMETALATED ARYL GROUP AND THEIR USE IN ORGANIC LIGHT EMITTING DIODES | UDC IRELAND LTD (IE) | 2021-11-10 | — | — | EP | disclosed |
| US-10370396-B2 | Metal complexes, comprising carbene ligands having an O-substituted non-cyclometallated aryl group and their use in organic light emitting diodes | UDC IRELAND LIMITED (IE) | 2019-08-06 | — | — | US | disclosed |
| US-20190016740-A1 | Metal Complexes, Comprising Carbene Ligands Having an O-Substituted Non-Cyclometalated Aryl Group and Their Use in Organic Light Emitting Diodes | UDC IRELAND LTD (IE) | 2019-01-17 | — | — | US | disclosed |
| US-20180127448-A1 | Metal Complexes, Comprising Carbene Ligands Having an O-Substituted Non-Cyclometalated Aryl Group and Their Use in Organic Light Emitting Diodes | UDC IRELAND LTD (IE) | 2018-05-10 | — | — | US | disclosed |
| US-20180127448-A1 | Metal Complexes, Comprising Carbene Ligands Having an O-Substituted Non-Cyclometalated Aryl Group and Their Use in Organic Light Emitting Diodes | UDC IRELAND LTD (IE) | 2018-05-10 | — | — | US | disclosed |
| US-9862739-B2 | Metal complexes, comprising carbene ligands having an O-substituted non-cyclometalated aryl group and their use in organic light emitting diodes | UDC IRELAND LIMITED (IE) | 2018-01-09 | — | — | US | disclosed |
| US-20170183367-A1 | Metal Complexes, Comprising Carbene Ligands Having an O-Substituted Non-Cyclometalated Aryl Group and Their Use in Organic Light Emitting Diodes | UDC IRELAND LIMITED (IE) | 2017-06-29 | — | — | US | disclosed |
| US-20170183367-A1 | Metal Complexes, Comprising Carbene Ligands Having an O-Substituted Non-Cyclometalated Aryl Group and Their Use in Organic Light Emitting Diodes | UDC IRELAND LIMITED (IE) | 2017-06-29 | — | — | US | disclosed |
| WO-2015150203-A1 | METAL COMPLEXES, COMPRISING CARBENE LIGANDS HAVING AN O-SUBSTITUTED NON-CYCLOMETALATED ARYL GROUP AND THEIR USE IN ORGANIC LIGHT EMITTING DIODES | BASF SE (DE) | 2015-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170183367-A1 | Metal Complexes, Comprising Carbene Ligands Having an O-Substituted Non-Cyclometalated Aryl Group and Their Use in Organic Light Emitting Diodes | ICOSLG, CD40LG, OCIAD1 | AURKA 2664/4885KDM4E 3918/4885ATM 3309/4885 |
| US-20190016740-A1 | Metal Complexes, Comprising Carbene Ligands Having an O-Substituted Non-Cyclometalated Aryl Group and Their Use in Organic Light Emitting Diodes | ICOSLG, CD40LG, OCIAD1 | AURKA 2664/4885KDM4E 3918/4885ATM 3309/4885 |
| US-10370396-B2 | Metal complexes, comprising carbene ligands having an O-substituted non-cyclometallated aryl group and their use in organic light emitting diodes | ICOSLG, CD40LG, OCIAD1 | AURKA 2785/4885KDM4E 3913/4885ATM 3363/4885 |
| US-20180127448-A1 | Metal Complexes, Comprising Carbene Ligands Having an O-Substituted Non-Cyclometalated Aryl Group and Their Use in Organic Light Emitting Diodes | ICOSLG, CD40LG, OCIAD1 | AURKA 2664/4885KDM4E 3918/4885ATM 3309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.