Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 12/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CD74 | P04233 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17156114 | 0.84 | MIF (1.00) | MIFALDH1A1MAPK1CD74POLB | |
| SCHEMBL17156435 | 0.84 | MIF (0.81) | MIFALDH1A1MAPK1CD74POLB | |
| SCHEMBL17156221 | 0.83 | MIF (0.68) | MIFALDH1A1MAPK1CD74POLB | |
| SCHEMBL17165038 | 0.83 | MIF (0.57) | MIFALDH1A1POLBIDO1SMN1; SMN2 | |
| SCHEMBL17156099 | 0.83 | IDO1 (0.71) | MIFCD74POLBIDO1MEN1 | |
| SCHEMBL17261583 | 0.80 | MIF (0.72) | MIFALDH1A1MAPK1POLBIDO1 | |
| SCHEMBL18418411 | 0.80 | MIF (0.58) | MIFALDH1A1MAPK1POLBIDO1 | |
| SCHEMBL17156190 | 0.80 | POLB (0.73) | MIFCD74POLBMEN1KMT2A | |
| SCHEMBL17156133 | 0.78 | MIF (0.51) | MIFALDH1A1POLBIDO1MEN1 | |
| SCHEMBL17156177 | 0.78 | KMT2A (0.51) | MIFALDH1A1POLBIDO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10160732-B2 | MIF inhibitors | MIFCARE (FR) | 2018-12-25 | — | — | US | claimed |
| EP-2929882-B1 | MIF inhibitors | MIFCARE (FR) | 2018-06-13 | — | — | EP | claimed |
| US-20170029387-A1 | MIF INHIBITORS | APAXEN (BE) | 2017-02-02 | — | — | US | claimed |
| WO-2015155358-A1 | MIF INHIBITORS | MIFCARE (FR) | 2015-10-15 | — | — | WO | claimed |
| EP-2929882-A1 | MIF inhibitors | Mifcare (FR) | 2015-10-14 | — | — | EP | claimed |
| US-10160732-B2 | MIF inhibitors | MIFCARE (FR) | 2018-12-25 | — | — | US | disclosed |
| EP-2929882-B1 | MIF inhibitors | MIFCARE (FR) | 2018-06-13 | — | — | EP | disclosed |
| US-20170029387-A1 | MIF INHIBITORS | APAXEN (BE) | 2017-02-02 | — | — | US | disclosed |
| US-20170029387-A1 | MIF INHIBITORS | APAXEN (BE) | 2017-02-02 | — | — | US | disclosed |
| US-20170029387-A1 | MIF INHIBITORS | APAXEN (BE) | 2017-02-02 | — | — | US | disclosed |
| WO-2015155358-A1 | MIF INHIBITORS | MIFCARE (FR) | 2015-10-15 | — | — | WO | disclosed |
| EP-2929882-A1 | MIF inhibitors | Mifcare (FR) | 2015-10-14 | — | — | EP | disclosed |
| EP-2929882-A1 | MIF inhibitors | Mifcare (FR) | 2015-10-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10160732-B2 | MIF inhibitors | MIF, MSR1, MMP12 | MIF 1/4885ALDH1A1 886/4885MAPK1 914/4885 |
| US-20170029387-A1 | MIF INHIBITORS | MIF, MSR1, MMP12 | MIF 1/4885ALDH1A1 886/4885MAPK1 914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.